Question · asked by 1 review

Chlorhexidine vs povidone‐iodine: Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity

Population
Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
Intervention
Chlorhexidine
Comparison
povidone‐iodine
Outcome
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity

It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with povidone iodine (very low certainty).

What each review found

Include earlier review versions
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
Chlorhexidine (CHX) vs Povidone iodine
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them · operator level; aerobic and anaerobic cultures combined
It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with povidone iodine (very low certainty).
Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental… (2022) · Cochrane All outcomes
MD -4.7 [-7.01, -2.39]1 study · 30 participantsVery low
Chlorhexidine (CHX) vs Povidone iodine
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them · operator level; aerobic cultures
It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with povidone iodine (very low certainty).
Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental… (2022) · Cochrane All outcomes
MD -10.75 [-26.24, 4.74]2 studies · 52 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental healthcare providers
2022 · Cochrane All outcomes
2022-02Not listedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.