Question · asked by 1 review
Chlorhexidine vs Cetylpyridinium chloride (CPC): Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity
- Population
- Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
- Intervention
- Chlorhexidine
- Comparison
- Cetylpyridinium chloride (CPC)
- Outcome
- Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity
It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with cetylpyridinium chloride (CPC) (very low certainty).
What each review found
Include earlier review versionsNo studies found 0 · 0%GRADE not reported 0 · 0%Very low 9 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Chlorhexidine (CHX) vs Cetylpyridinium chloride (CPC) Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them · cold CHX vs cold CPC; assistant level It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with cetylpyridinium chloride (CPC) (very low certainty). Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental… (2022) · Cochrane All outcomes | MD 8.8 [2.7, 14.9] | 1 study · 20 participants | Very low |
Chlorhexidine (CHX) vs Cetylpyridinium chloride (CPC) Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them · cold CHX vs tempered CPC; assistant level It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with cetylpyridinium chloride (CPC) (very low certainty). Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental… (2022) · Cochrane All outcomes | MD 17.4 [11.3, 23.5] | 1 study · 20 participants | Very low |
Chlorhexidine (CHX) vs Cetylpyridinium chloride (CPC) Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them · tempered CHX vs cold CPC; operator level It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with cetylpyridinium chloride (CPC) (very low certainty). Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental… (2022) · Cochrane All outcomes | MD -11.5 [-18.37, -4.63] | 1 study · 20 participants | Very low |
Chlorhexidine (CHX) vs Cetylpyridinium chloride (CPC) Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them · tempered CHX vs cold CPC; assistant level It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with cetylpyridinium chloride (CPC) (very low certainty). Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental… (2022) · Cochrane All outcomes | MD -8.8 [-14.9, -2.7] | 1 study · 20 participants | Very low |
Chlorhexidine (CHX) vs Cetylpyridinium chloride (CPC) Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them · tempered CHX vs tempered CPC; operator level It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with cetylpyridinium chloride (CPC) (very low certainty). Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental… (2022) · Cochrane All outcomes | MD -2.2 [-9.07, 4.67] | 1 study · 20 participants | Very low |
Chlorhexidine (CHX) vs Cetylpyridinium chloride (CPC) Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them · CHX 0.12% vs CPC+Zn+F; operator level It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with cetylpyridinium chloride (CPC) (very low certainty). Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental… (2022) · Cochrane All outcomes | MD -30 [-85.86, 25.86] | 1 study · 30 participants | Very low |
Chlorhexidine (CHX) vs Cetylpyridinium chloride (CPC) Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them · tempered CHX vs tempered CPC; assistant level It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with cetylpyridinium chloride (CPC) (very low certainty). Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental… (2022) · Cochrane All outcomes | MD -0.2 [-6.3, 5.9] | 1 study · 20 participants | Very low |
Chlorhexidine (CHX) vs Cetylpyridinium chloride (CPC) Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them · cold CHX vs tempered CPC; operator level It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with cetylpyridinium chloride (CPC) (very low certainty). Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental… (2022) · Cochrane All outcomes | MD 13.6 [6.73, 20.47] | 1 study · 20 participants | Very low |
Chlorhexidine (CHX) vs Cetylpyridinium chloride (CPC) Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them · cold CHX vs cold CPC; operator level It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with cetylpyridinium chloride (CPC) (very low certainty). Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental… (2022) · Cochrane All outcomes | MD 4.43 [-2.27, 11.13] | 2 studies · 50 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental healthcare providers 2022 · Cochrane All outcomes | 2022-02 | Not listed | Not assessed |
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How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.