Cochrane · intervention · CD003069
Interventions for replacing missing teeth: maintaining and recovering soft tissue health around dental implants
Grusovin, MG, Coulthard, P, Worthington, HV, et al. · Cochrane Database of Systematic Reviews · 2010 · Cochrane Library
Full textEvery question was extracted from the full review (methods and results), not only its Summary of Findings table.
Questions
32
current version
GRADE rated
0
No studies
0
Included studies
11
as reported
No studies 0 · 0%Ungraded 32 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Adults who have dental implants; (1) healthy peri-implant soft tissues at baseline (maintaining); (2) peri-implant mucositis lesions at baseline (recovering: bleeding on marginal probing and/or pockets with bone loss <=2.5 mm) | Adults with dental implants (healthy tissues or peri-implant mucositis); USA (3), Netherlands (2), New Zealand (1), Sweden (3), Israel (1), Portugal (1); 319 patients |
| Intervention | (1) Interventions for maintaining peri-implant soft tissue health (self / professionally administered); (2) Interventions for recovering peri-implant soft tissue health (self / professionally administered). Active agents: oral hygiene procedures; local or systemic therapeutic agents; other interventions | Powered toothbrushing (n=40); Hyaluronic acid gel (n=30); Amine fluoride/stannous fluoride mouthwash (n=33); Phosphoric etching gel (n=16); Chlorhexidine solution enclosed in implants (n=12); Sonic toothbrushing (n=31); Listerine mouthwash (n=20); Subgingival chlorhexidine irrigation (n=24); Topical minocycline (n=32); Triclosan dentifrice (n=59); Titanium curette debridement (n=31) |
| Comparison | Placebo; No treatment; Another active intervention | Manual toothbrushing (n=40); Chlorhexidine gel (n=30); Chlorhexidine mouthwash (n=33); Mechanical debridement (n=16); Physiologic solution (n=12); Manual toothbrushing (n=31); Placebo mouthwash (n=20); Chlorhexidine mouthwash (n=24); Chlorhexidine gel (n=32); Sodium fluoride dentifrice (n=59); Ultrasonic device debridement (n=31) |
| Outcomes | Implant failure; Radiographic marginal bone level changes; Changes in probing attachment level; Changes in probing pocket depth; Marginal bleeding; Plaque; Side effects; Ease of maintenance; Patient satisfaction; Cost; Treatment time | Plaque (n=264); Marginal bleeding (n=74); Changes in probing pocket depth; Probing attachment level (n=20); Implant failure (n=122); Change in taste (n=33); Staining index (n=33); Patient satisfaction (n=64); Ease of maintenance (n=31); Soreness in the gums (n=32); Side effects/pain (n=16) |
| Study designs | Randomised controlled trials (parallel group, split-mouth and cross-over designs) | 8 parallel group; 2 split-mouth; 1 cross-over (all RCTs) |
| Timing | Not specified | 6 weeks to 1 year |
Search date: 2010-06-02. Databases: Cochrane Oral Health Group's Trials Register; Cochrane Central Register of Controlled Trials (CENTRAL); MEDLINE; EMBASE
Questions and results
Show all 4 versionsPowered toothbrushing vs Manual toothbrushing
Population: Adults with dental implants and healthy peri-implant soft tissues at baseline
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Change in probing pocket depth 6 weeks | At 6 weeks there was no significant difference in change of probing pocket depths | 1 study · 40 participants | Ungraded |
Plaque 6 weeks | MD 0.10 [-0.66, 0.86] | 1 study · 40 participants | Ungraded |
Sonic toothbrushing vs Manual toothbrushing
Population: Adults with dental implants and peri-implant mucositis at baseline
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Patient satisfaction (liked toothbrush) 6 months | RR 1.48 [1.03, 2.13] | 1 study · 31 participants | Ungraded |
Ease of maintenance 6 months | RR 0.94 [0.79, 1.12] | 1 study · 31 participants | Ungraded |
Plaque 6 months | MD -0.14 [-0.47, 0.19] | 1 study · 31 participants | Ungraded |
Change in probing pocket depth 6 months | MD 0.08 [-0.64, 0.80] | 1 study · 31 participants | Ungraded |
Listerine mouthwash vs Placebo mouthwash
Population: Adults with dental implants and peri-implant mucositis at baseline
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Marginal bleeding 3 months | MD -0.20 [-0.25, -0.15] | 1 study · 20 participants | Ungraded |
Plaque 3 months | MD -0.88 [-0.93, -0.83] | 1 study · 20 participants | Ungraded |
Probing pocket depth 3 months | MD 0.15 [0.06, 0.24] | 1 study · 20 participants | Ungraded |
Probing attachment level 3 months | MD 0.07 [-0.11, 0.25] | 1 study · 20 participants | Ungraded |
Subgingival chlorhexidine irrigation vs Chlorhexidine mouthwash
Population: Adults with dental implants and peri-implant mucositis at baseline
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Marginal bleeding 3 months | MD -0.17 [-0.19, -0.15] | 1 study · 24 participants | Ungraded |
Plaque 3 months | MD -0.20 [-0.24, -0.16] | 1 study · 24 participants | Ungraded |
Phosphoric etching (acid) gel vs Mechanical debridement and polishing
Population: Adults with dental implants and healthy peri-implant soft tissues at baseline
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Cleaning/treatment time 5 months | Both interventions took a similar time to administer (no statistically significant difference in cleaning time) | 1 study · 16 participants | Ungraded |
Side effects (pain) 5 months | Nine out of 16 patients reported slight (7) to moderate (2) pain at the etching gel side compared to none in the debridement group (P < 0.001) | 1 study · 16 participants | Ungraded |
Change in probing pocket depth 5 months | MD 0.28 [-1.97, 2.53] | 1 study · 16 participants | Ungraded |
Plaque 5 months | MD 0.00 [-0.33, 0.33] | 1 study · 16 participants | Ungraded |
Hyaluronic acid gel (brushing) vs Chlorhexidine gel (brushing)
Population: Adults with dental implants and healthy peri-implant soft tissues at baseline
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Marginal bleeding 6 months | MD 0.20 [-0.28, 0.68] | 1 study · 30 participants | Ungraded |
Plaque 6 months | MD -0.47 [-1.08, 0.14] | 1 study · 30 participants | Ungraded |
Change in probing pocket depth 6 months | MD 0.00 [-0.65, 0.65] | 1 study · 30 participants | Ungraded |
Amine fluoride/stannous fluoride (AmF/SnF2) mouthwash vs Chlorhexidine mouthwash
Population: Adults with dental implants and healthy peri-implant soft tissues at baseline
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Staining index 3 months | MD 0.06 [-0.10, 0.22] | 1 study · 33 participants | Ungraded |
Implant failure 3 months | RR 0.28 [0.01, 6.43] | 1 study · 33 participants | Ungraded |
Change in taste 3 months | MD -0.55 [-1.02, -0.08] | 1 study · 33 participants | Ungraded |
Patient satisfaction (desire for future use) 3 months | MD 2.08 [1.52, 2.64] | 1 study · 33 participants | Ungraded |
Chlorhexidine solution enclosed in implant inner part vs Physiologic (saline) solution
Population: Adults with dental implants and healthy peri-implant soft tissues at baseline
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Plaque 6 weeks | MD 0.00 [-0.48, 0.48] | 1 study · 12 participants | Ungraded |
Mechanical debridement plus topical minocycline vs Mechanical debridement plus chlorhexidine gel
Population: Adults with dental implants and peri-implant mucositis at baseline
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Plaque 12 months | MD 6.00 [-9.07, 21.07] | 1 study · 32 participants | Ungraded |
Change in probing pocket depth 12 months | MD 0.30 [-0.17, 0.77] | 1 study · 32 participants | Ungraded |
Change in probing pocket depth (worst sites) 12 months | MD 0.40 [-0.28, 1.08] | 1 study · 32 participants | Ungraded |
Soreness in the gums 12 months | RR 5.00 [0.66, 38.15] | 1 study · 32 participants | Ungraded |
Triclosan dentifrice vs Sodium fluoride dentifrice
Population: Adults with dental implants and peri-implant mucositis at baseline
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Change in probing pocket depth (>=4 mm) 6 months | MD 0.30 [-0.06, 0.66] | 1 study · 59 participants | Ungraded |
Plaque 6 months | MD -7.50 [-17.52, 2.52] | 1 study · 59 participants | Ungraded |
Mechanical debridement with titanium curettes vs Mechanical debridement with ultrasonic device
Population: Adults with dental implants and peri-implant mucositis at baseline
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Plaque 6 months | MD 5.00 [-21.21, 31.21] | 1 study · 31 participants | Ungraded |
Change in probing pocket depth 6 months | MD -0.40 [-1.14, 0.34] | 1 study · 31 participants | Ungraded |