Question · asked by 1 review
Chlorhexidine mouthwash vs placebo: Cariogenic bacteria (Mutans streptococci)
- Population
- People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
- Intervention
- Chlorhexidine mouthwash
- Comparison
- placebo
- Outcome
- Cariogenic bacteria (Mutans streptococci)
Chlorhexidine mouthwash reduced Mutans streptococci versus placebo, but certainty is very low.
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Chlorhexidine mouthwash vs Placebo Cariogenic bacteria (Mutans streptococci) · Orthodontic patients · ≤ 3 months Chlorhexidine mouthwash reduced Mutans streptococci versus placebo, but certainty is very low. The efficacy of mouthwashes on oral microorganisms and gingivitis in patients undergoing orthodontic… (2023) All outcomes | Colony count of MS was significantly reduced compared to placebos according to three studies [34; 48; 52]; colony count of MS was slightly reduced compared to placebo in a short time in one study [40]. | 4 studies | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| The efficacy of mouthwashes on oral microorganisms and gingivitis in patients undergoing orthodontic treatment: a systematic review and… 2023 All outcomes | 16 April 2022 (databases and grey literature searched by 16 April 2022; no publication-year limit) | 47 | Low / Moderate |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Chlorhexidine mouthwash vs Blank control · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies) · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.