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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

15,213 questions in 2,394 reviews

current versions
No studies 15,213 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Intervention NR
Cancer occurrence
Chinese herbal medicines for benign thyroid nodules in adults (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Health‐related quality of life
Chinese herbal medicines for benign thyroid nodules in adults (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Pressure symptoms/cosmetic complaints
Chinese herbal medicines for benign thyroid nodules in adults (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Nodule volume reduction ≥ 50%
Chinese herbal medicines for benign thyroid nodules in adults (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Socioeconomic effects
Chinese herbal medicines for benign thyroid nodules in adults (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Primary: Child Intellectual development (attainment of educational goals) · children younger than five years of age
Centre‐based day care for children younger than five years of age in low‐ and middle‐income countries (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Secondary: Child behaviour · children younger than five years of age
Centre‐based day care for children younger than five years of age in low‐ and middle‐income countries (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Secondary: Disrupted child attachment · children younger than five years of age
Centre‐based day care for children younger than five years of age in low‐ and middle‐income countries (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Secondary: Paid parental employment · children younger than five years of age
Centre‐based day care for children younger than five years of age in low‐ and middle‐income countries (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Severe allergic reaction · persons with severe haemophilia A and factor inhibitory antibodies
Immune tolerance induction for treating inhibitors in people with congenital haemophilia A or B (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Nephrotic symdrome · persons with severe haemophilia A and factor inhibitory antibodies
Immune tolerance induction for treating inhibitors in people with congenital haemophilia A or B (2014) · Cochrane
no estimate extractedNRNo studies
Tricyclic antidepressants vs placebo
Acceptability (all‐cause drop‐outs) · somatoform disorders in adults
Pharmacological interventions for somatoform disorders in adults (2014) · Cochrane
no estimate extractedNRNo studies
Natural products vs placebo
Functional disability and quality of life (post‐treatment score on self report scales) · somatoform disorders in adults
Pharmacological interventions for somatoform disorders in adults (2014) · Cochrane
no estimate extractedNRNo studies
Tricyclic antidepressants vs another medication
Functional disability and quality of life · somatoform disorders in adults
Pharmacological interventions for somatoform disorders in adults (2014) · Cochrane
no estimate extractedNRNo studies
Tricyclic antidepressants vs placebo
Anxiety (post‐treatment score on self report and clinician‐rated scales) · somatoform disorders in adults
Pharmacological interventions for somatoform disorders in adults (2014) · Cochrane
no estimate extractedNRNo studies
Antidepressants vs a combination of medications
Adverse effects (drop‐outs due to adverse effects) · somatoform disorders in adults
Pharmacological interventions for somatoform disorders in adults (2014) · Cochrane
no estimate extractedNRNo studies
Antidepressants vs a combination of medications
Treatment response (post‐treatment score on self report and clinician‐rated scales) · somatoform disorders in adults
Pharmacological interventions for somatoform disorders in adults (2014) · Cochrane
no estimate extractedNRNo studies
Antidepressants vs a combination of medications
Functional disability and quality of life · somatoform disorders in adults
Pharmacological interventions for somatoform disorders in adults (2014) · Cochrane
no estimate extractedNRNo studies
Tricyclic antidepressants vs placebo
Depression (post‐treatment score on self report and clinician‐rated scales) · somatoform disorders in adults
Pharmacological interventions for somatoform disorders in adults (2014) · Cochrane
no estimate extractedNRNo studies
Tricyclic antidepressants vs placebo
Adverse effects (drop‐outs due to adverse effects) · somatoform disorders in adults
Pharmacological interventions for somatoform disorders in adults (2014) · Cochrane
no estimate extractedNRNo studies
Tricyclic antidepressants vs placebo
Treatment response (post‐treatment score on self report and clinician‐rated scales) · somatoform disorders in adults
Pharmacological interventions for somatoform disorders in adults (2014) · Cochrane
no estimate extractedNRNo studies
Tricyclic antidepressants vs placebo
Functional disability and quality of life (post‐treatment score on self report and clinician‐rated scales) · somatoform disorders in adults
Pharmacological interventions for somatoform disorders in adults (2014) · Cochrane
no estimate extractedNRNo studies
Alcohol ban vs no ban
Delayed age of initiation of alcohol use ‐ not reported · General population
Restricting or banning alcohol advertising to reduce alcohol consumption in adults and adolescents (2014) · Cochrane
no estimate extractedNRNo studies
Alcohol ban vs no ban
Reduction in alcohol‐related injuries or accidents ‐ not reported · General population
Restricting or banning alcohol advertising to reduce alcohol consumption in adults and adolescents (2014) · Cochrane
no estimate extractedNRNo studies
Alcohol ban vs no ban
Reduction in individual spending on alcohol ‐ not reported · General population
Restricting or banning alcohol advertising to reduce alcohol consumption in adults and adolescents (2014) · Cochrane
no estimate extractedNRNo studies
Alcohol ban vs no ban
Loss of revenue from alcohol industry ‐ not reported · General population
Restricting or banning alcohol advertising to reduce alcohol consumption in adults and adolescents (2014) · Cochrane
no estimate extractedNRNo studies
Alcohol ban vs no ban
Loss of advertising revenue ‐ not reported · General population
Restricting or banning alcohol advertising to reduce alcohol consumption in adults and adolescents (2014) · Cochrane
no estimate extractedNRNo studies
Non‐alcohol commercials vs alcohol commercials
Delayed age of initiation of alcohol use ‐ not measured · General population
Restricting or banning alcohol advertising to reduce alcohol consumption in adults and adolescents (2014) · Cochrane
no estimate extractedNRNo studies
Non‐alcohol commercials vs alcohol commercials
Reduction in rate of reported risk behaviour ‐ not measured · General population
Restricting or banning alcohol advertising to reduce alcohol consumption in adults and adolescents (2014) · Cochrane
no estimate extractedNRNo studies
Non‐alcohol commercials vs alcohol commercials
Reduction in alcohol‐related injuries or accidents ‐ not measured · General population
Restricting or banning alcohol advertising to reduce alcohol consumption in adults and adolescents (2014) · Cochrane
no estimate extractedNRNo studies
Non‐alcohol commercials vs alcohol commercials
Reduction in individual spending on alcohol ‐ not measured · General population
Restricting or banning alcohol advertising to reduce alcohol consumption in adults and adolescents (2014) · Cochrane
no estimate extractedNRNo studies
Non‐alcohol commercials vs alcohol commercials
Loss of revenue from alcohol industry ‐ not measured · General population
Restricting or banning alcohol advertising to reduce alcohol consumption in adults and adolescents (2014) · Cochrane
no estimate extractedNRNo studies
Non‐alcohol commercials vs alcohol commercials
Loss of advertising revenue ‐ not measured · General population
Restricting or banning alcohol advertising to reduce alcohol consumption in adults and adolescents (2014) · Cochrane
no estimate extractedNRNo studies
Alcohol ban vs no ban
Reduction in rate of reported risk behaviour ‐ not reported · General population
Restricting or banning alcohol advertising to reduce alcohol consumption in adults and adolescents (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Health‐related quality of life · participants with asthma
Vitamins C and E for asthma and exercise‐induced bronchoconstriction (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Asthma exacerbation as defined by hospital admission or treatment with a course of oral corticosteroids · participants with asthma
Vitamins C and E for asthma and exercise‐induced bronchoconstriction (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Health‐related quality of life · participants with exercise‐induced asthma
Vitamins C and E for asthma and exercise‐induced bronchoconstriction (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Asthma exacerbation as defined by hospital admission or treatment with a course of oral corticosteroids · participants with exercise‐induced asthma
Vitamins C and E for asthma and exercise‐induced bronchoconstriction (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adverse events · participants with exercise‐induced asthma
Vitamins C and E for asthma and exercise‐induced bronchoconstriction (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
At least 50% reduction in pain or equivalent · neuropathic pain (5 studies in painful diabetic neuropathy and polyneuropathy)
Imipramine for neuropathic pain in adults (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
"Moderate" benefit At least 30% reduction in pain · neuropathic pain (5 studies in painful diabetic neuropathy and polyneuropathy)
Imipramine for neuropathic pain in adults (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Proportion below 30/100 mm on VAS · neuropathic pain (5 studies in painful diabetic neuropathy and polyneuropathy)
Imipramine for neuropathic pain in adults (2014) · Cochrane
no estimate extractedNRNo studies
Azapirone vs placebo
Rate of 'response' · adults with panic disorder
Azapirones versus placebo for panic disorder in adults (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Proportion below 30/100 mm on VAS · neuropathic pain (6 studies in central neuropathic pain due to multiple sclerosis, spinal cord injury, polyneuropathy,…
Levetiracetam for neuropathic pain in adults (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Patient Global Impression of Change much or very much improved · adults with peripheral neuropathic pain conditions
Topical lidocaine for neuropathic pain in adults (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
At least 50% reduction in pain · adults with neuropathic pain (3 studies in painful diabetic neuropathy and postherpetic neuralgia)
Desipramine for neuropathic pain in adults (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
At least 30% reduction in pain · adults with neuropathic pain (3 studies in painful diabetic neuropathy and postherpetic neuralgia)
Desipramine for neuropathic pain in adults (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Proportion below 30/100 mm on VAS · adults with neuropathic pain (3 studies in painful diabetic neuropathy and postherpetic neuralgia)
Desipramine for neuropathic pain in adults (2014) · Cochrane
no estimate extractedNRNo studies
Laser photocoagulation vs control
Quality of life · people with diabetic retinopathy
Laser photocoagulation for proliferative diabetic retinopathy (2014) · Cochrane
no estimate extractedNRNo studies
Laser photocoagulation vs control
Pain · people with diabetic retinopathy
Laser photocoagulation for proliferative diabetic retinopathy (2014) · Cochrane
no estimate extractedNRNo studies