Cochrane · systematic review · CD010749

Vitamins C and E for asthma and exercise‐induced bronchoconstriction

Wilkinson, M, Hart, A, Milan, SJ, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
9
current version
GRADE rated
4
No studies
5
Included studies
NR
No studies 5 · 55.6%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 33.3%Moderate 1 · 11.1%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Comparison

Population: participants with asthma
5 questions
OutcomeEffectEvidenceStatus / GRADE
Health‐related quality of life
no estimate extractedNRNo studies
Asthma exacerbation as defined by hospital admission or treatment with a course of oral corticosteroids
no estimate extractedNRNo studies
Lung function (FEV1, PEF)
no estimate extracted3 studies · 192 participantsModerate
Downgraded: risk of bias
Symptoms
no estimate extracted1 study · 15 participantsLow
Downgraded: risk of bias
Adverse events
no estimate extracted1 study · 15 participantsLow
Downgraded: risk of bias

Comparison

Population: participants with exercise‐induced asthma
4 questions
OutcomeEffectEvidenceStatus / GRADE
Health‐related quality of life
no estimate extractedNRNo studies
Asthma exacerbation as defined by hospital admission or treatment with a course of oral corticosteroids
no estimate extractedNRNo studies
Lung function (FEV1, PEF)
no estimate extracted1 study · 8 participantsLow
Downgraded: risk of bias
Adverse events
no estimate extractedNRNo studies