Cochrane · systematic review · CD011234

Laser photocoagulation for proliferative diabetic retinopathy

Evans, JR, Michelessi, M, Virgili, G · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
4
No studies
3
Included studies
NR
No studies 3 · 42.9%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 42.9%Moderate 1 · 14.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Laser photocoagulation compared to control for diabetic retinopathy

Population: people with diabetic retinopathy
7 questions
OutcomeEffectEvidenceStatus / GRADE
Loss of 15 or more letters BCVA
Laser photocoagulation vs control
RR 0.99 [0.89, 1.11]2 studies · 8926 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
BCVA measured using logMAR acuity (0 = 6/6 visual acuity, higher score is worse visual acuity)
Laser photocoagulation vs control
no estimate extracted1 study · 36 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Severe visual loss (BCVA < 6/60)
Laser photocoagulation vs control
RR 0.46 [0.24, 0.86]4 studies · 9276 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Progression of diabetic retinopathy
Laser photocoagulation vs control
RR 0.49 [0.37, 0.64]4 studies · 8331 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Quality of life
Laser photocoagulation vs control
no estimate extractedNRNo studies
Pain
Laser photocoagulation vs control
no estimate extractedNRNo studies
Loss of driving licence
Laser photocoagulation vs control
no estimate extractedNRNo studies