Cochrane · systematic review · CD010958
Topical lidocaine for neuropathic pain in adults
Derry, S, Wiffen, PJ, Moore, RA, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
Pain, Palliative and Supportive CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
4
No studies
1
Included studies
NR
No studies 1 · 16.7%Ungraded 1 · 16.7%Very low 4 · 66.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: adults with peripheral neuropathic pain conditions
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
At least 50% reduction in pain or equivalent | no estimate extracted | 1 study · 58 participants | Very low |
"Moderate" benefit At least 30% reduction in pain | no estimate extracted | 1 study · 58 participants | Very low |
Patient Global Impression of Change much or very much improved | no estimate extracted | NR | No studies |
Adverse event withdrawals | no estimate extracted | 1 study · 263 participants | Very low |
Serious adverse events | no estimate extracted | 1 study · 263 participants | Very low |
Death | no estimate extracted | 5 studies · 210 participants | Ungraded |