Probing pocket depth · Adults (general and hospital populations assessed in case-control studies)
Probing depth is significantly increased in systemic sclerosis patients (SMD 3.10) with very high heterogeneity; certainty ungraded.
3 findings from 1 review
SMD 3.101 [1.374, 4.829]
7 studies
GRADE not reported
Oral manifestations of patients with systemic sclerosis: a meta-analysis for case-controlled studies. 2021 All outcomesHospital/clinic-based case-control studies from Asia, America and Europe · Other/non-Asia (Da Silva 2019, Iordache 2019, Isola 2017, Pischon 2016)
SMD 4.86 [1.61, 8.10]
4 studies
GRADE not reported
Oral manifestations of patients with systemic sclerosis: a meta-analysis for case-controlled studies. 2021 All outcomesHospital/clinic-based case-control studies from Asia, America and Europe · Asia (Elimelech 2015, Leung 2011, Mayer 2013)
SMD 1.113 [0.751, 1.476]
3 studies
GRADE not reported
Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
17 findings from 1 review
Show 14 more findings
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Dentine-caries (D3) prevalence low <15% (non-CBCT)
Sensitivity 0.36 [0.25, 0.47]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Reference standard: excavation (non-CBCT)
Sensitivity 0.51 [0.27, 0.74]
5 studies
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Analogue and digital combined (non-CBCT); 97 datasets
Sensitivity 0.46 [0.40, 0.51]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Dentine-caries (D3) prevalence high >=35% or unreported (non-CBCT)
Sensitivity 0.50 [0.40, 0.59]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Sensitivity analysis: low risk of bias for index test
Sensitivity 0.51 [0.43, 0.61]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Sensitivity analysis: excluding high/unclear risk of bias reference standard
Sensitivity 0.51 [0.45, 0.57]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Setting: in vivo / clinical (non-CBCT)
Sensitivity 0.56 [0.43, 0.69]
17 studies
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Setting: in vitro (non-CBCT)
Sensitivity 0.44 [0.37, 0.50]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Sensitivity analysis: low dentine-caries prevalence <15%
Sensitivity 0.34 [0.25, 0.45]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Reference standard: histology (non-CBCT)
Sensitivity 0.46 [0.39, 0.53]
64 studies
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies)
Sensitivity 0.47 [0.40, 0.53]
77 studies
Low
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Occlusal surfaces (non-CBCT)
Sensitivity 0.45 [0.35, 0.54]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Primary dentition (non-CBCT)
Sensitivity 0.52 [0.40, 0.63]
Studies not reported
GRADE not reported
Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Proximal surfaces (non-CBCT)
Sensitivity 0.47 [0.39, 0.55]
Studies not reported
GRADE not reported
Diagnostic accuracy for proximal caries detection (dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro)
Under in vitro conditions, conventional E-speed bitewing radiography had a pooled diagnostic odds ratio of 31.40 (95% CI 14.31, 68.93) for proximal caries detection at the dentin detection level; ungraded.
4 findings from 1 review
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Sensitivity for detection of enamel caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
10 findings from 1 review
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Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…
It is very uncertain whether non-selective carious tissue removal and conventional restoration (CR) changes failure of therapy compared with selective carious tissue removal (selective excavation, SE) (very low certainty).
3 findings from 1 review
Diagnostic accuracy for proximal caries detection (dentin detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo)
Under in vivo conditions, phosphor-plate digital bitewing radiography had a pooled specificity of 0.60 (95% CI 0.20, 0.90) for proximal caries detection at the dentin detection level; ungraded.
4 findings from 1 review
Show 1 more finding
Specificity for detection of enamel caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review
Dental caries prevalence · Preschool children in Sharjah day cares
Caries prevalence was 77% in private day cares versus 22% in public day cares.
2 findings from 1 review
Diagnostic accuracy for proximal caries detection (dentin detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo)
Under in vivo conditions, laser fluorescence (DIAGNOdent 2190) had a pooled specificity of 0.60 (95% CI 0.15, 0.93) for proximal caries detection at the dentin detection level; ungraded.
4 findings from 1 review
Show 1 more finding
Dental caries in children · Children in cross-sectional studies from Europe
Maternal smoking during pregnancy was associated with higher odds of childhood caries in the Europe subgroup.
1 finding from 1 review
OR 1.55 [1.45, 1.66]
3 studies
GRADE not reported
Dental caries · Children aged 5-6 years in Ajman schools
High snack consumption was associated with higher mean DMFT.
1 finding from 1 review
Harms (toxicity and postoperative sensitivity) · People with permanent or adult posterior teeth requiring restoration (parallel-group trials involved children aged 6 to 12 years)
1 finding from 1 review
SoF (Harms, follow-up 2 weeks to 7 years): See comments; 3 studies; certainty very low (⊕⊝⊝⊝). Comments: data were reported for physical development, neurological and psychological effects, neurobehavioural and…
3 studies
Very low
Sites with probing depth >= 4 mm · Adults (general and hospital populations assessed in case-control studies)
Sites with probing depth >= 4 mm are significantly more frequent in SSc patients (SMD 2.07); certainty ungraded.
1 finding from 1 review
SMD 2.071 [0.267, 3.875]
3 studies
GRADE not reported
Specificity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
3 findings from 1 review
Difference in sensitivity · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies)
Imaging had lower sensitivity than visual classification in the fully within-person analysis.
1 finding from 1 review
Dental caries susceptibility · Children and adults (no age limit) assessed for dental caries susceptibility
No significant association between the TaqI (rs731236 T>C) polymorphism and dental caries for mixed dentition caries under the recessive (CC vs CT/TT) model (OR 1.23, 95% CI 0.66 to 2.29); ungraded.
6 findings from 1 review
Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. 2021 All outcomesCase-control studies of children and adults (China, India, Czech Republic, Turkey) · Dentition: Mixed dentition caries
OR 1.23 [0.66, 2.29]
2 studies · 270 participants
GRADE not reported
Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. 2021 All outcomesCase-control studies of children and adults (China, India, Czech Republic, Turkey) · Dentition: Deciduous tooth decay
OR 0.80 [0.05, 12.89]
2 studies · 929 participants
GRADE not reported
Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. 2021 All outcomesCase-control studies of children and adults (China, India, Czech Republic, Turkey) · Overall
OR 1.38 [1.03, 1.84]
7 studies · 2470 participants
GRADE not reported
Show 3 more findings
Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. 2021 All outcomesCase-control studies of children and adults (China, India, Czech Republic, Turkey) · Ethnicity: Caucasian
OR 1.33 [0.91, 1.95]
2 studies · 538 participants
GRADE not reported
Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. 2021 All outcomesCase-control studies of children and adults (China, India, Czech Republic, Turkey) · Dentition: Permanent tooth caries
OR 1.44 [1.03, 2.00]
3 studies · 1271 participants
GRADE not reported
Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. 2021 All outcomesCase-control studies of children and adults (China, India, Czech Republic, Turkey) · Ethnicity: Asian
OR 1.45 [0.93, 2.26]
5 studies · 1932 participants
GRADE not reported
Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review
Plaque/gingivitis visible in at least one oral region · School children aged 11-17 years in Sharjah
Plaque or gingivitis was visible in at least one oral region in 95% of participants.
1 finding from 1 review
Severe tooth wear prevalence · School children aged 2.6-6.8 years in Abu Dhabi
Severe tooth wear prevalence was 0.15%.
1 finding from 1 review
Diagnostic accuracy for proximal caries detection (dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro)
Under in vitro conditions, conventional F-speed bitewing radiography had a pooled diagnostic odds ratio of 8.7 (95% CI 4.2, 18.1) for proximal caries detection at the dentin detection level; ungraded.
4 findings from 1 review
Show 1 more finding