Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

316 questions · 321 findings · 136 reviews

No studies found 52 · 16.2%GRADE not reported 21 · 6.5%Very low 115 · 35.8%Low 92 · 28.7%Moderate 33 · 10.3%High 8 · 2.5%

Intervention not reported

Withdrawals due to adverse events · participants with rheumatoid arthritis and with partial response to MTX

The intervention showed no clear difference in withdrawals due to adverse events (moderate certainty).

1 finding from 1 review

Intervention not reported

Withdrawals due to adverse events · participants with rheumatoid arthritis and with a partial response to DMARDs

The intervention showed no clear difference in withdrawals due to adverse events (moderate certainty).

1 finding from 1 review

Skim milk enriched with GMP/G600 vs skim milk & lactose powder

Withdrawals due to adverse events · people with chronic gout

Skim milk enriched with GMP/G600 showed no clear difference in study withdrawals due to adverse events compared with skim milk, plus lactose powder (low certainty).

2 findings from 2 reviews · compare the 2 reviews

Testosterone vs placebo

Withdrawals due to adverse events · men with sexual dysfunction

It is very uncertain whether testosterone changes treatment withdrawal due to adverse events compared with placebo (very low certainty).

2 findings from 1 review

Paracetamol vs placebo

Withdrawals due to adverse events · Patients with osteoarthritis of the knee or hip

Paracetamol showed no clear difference in withdrawals due to adverse events 24 weeks compared with placebo (moderate certainty).

1 finding from 1 review