Intervention not reported
Serious adverse events · adults with fibromyalgia
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Findings
What do systematic reviews say?
1,337 questions · 1,354 findings · 566 reviews
No studies found 307 · 22.7%GRADE not reported 81 · 6%Very low 424 · 31.3%Low 310 · 22.9%Moderate 189 · 14%High 43 · 3.2%
Intervention not reported
Serious Adverse Events · patients with rheumatoid arthritis
The intervention showed no clear difference in serious Adverse Events (moderate certainty).
1 finding from 1 review
- RR 1.4 [0.36, 5.7]2 studies · 330 participantsModerate
LABA/ICS vs LTRA + ICS
Serious adverse events · patients with chronic asthma
LABA + ICS showed no clear difference in serious adverse events compared with LTRA + ICS (moderate certainty).
1 finding from 1 review
- Addition to inhaled corticosteroids of long‐acting beta₂‐agonists versus anti‐leukotrienes for chronic asthma 2014 · Cochrane Headline outcomes onlyRR 1.33 [0.99, 1.79]9 studies · 6288 participantsModerate
Other types of high tibial osteotomy (aHTO) vs closing wedge high tibial osteotomy (CW‐HTO)
Serious adverse events · patients with osteoarthritis of the knee
Other types of high tibial osteotomy (aHTO) showed no clear difference in serious adverse events compared with closing wedge high tibial osteotomy (CW‐HTO) (low certainty).
1 finding from 1 review
- RR 2.49 [0.64, 9.75]4 studies · 265 participantsLow
Sulfasalazine vs placebo
Serious adverse events · Patients with ankylosing spondylitis
Sulfasalazine showed no clear difference in serious adverse events compared with placebo (moderate certainty).
1 finding from 1 review
- OR 7.5 [0.15, 378.16]1 study · 264 participantsModerate
Intervention not reported
Serious adverse events · adults with neuropathic pain (Trigeminal neuralgia, painful diabetic neuropathy, chronic post stroke pain)
1 finding from 1 review
- Carbamazepine for chronic neuropathic pain and fibromyalgia in adults 2014 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 46 participantsVery low
Chinese herbal medicines vs no intervention
Serious adverse events · patients with osteoporosis
1 finding from 1 review
- no estimate extracted0 studies · 0 participantsGRADE not reported
Chinese herbal medicines vs Western medicine
Serious adverse events · patients with osteoporosis
1 finding from 1 review
- no estimate extracted0 studies · 0 participantsGRADE not reported
Chinese herbal medicines plus western medicine vs Western medicine
Serious adverse events · patients with osteoporosis
1 finding from 1 review
- no estimate extracted0 studies · 0 participantsGRADE not reported
Chinese herbal medicines vs placebo
Serious adverse events · patients with osteoporosis
1 finding from 1 review
- no estimate extracted0 studies · 0 participantsGRADE not reported
Allopurinol vs placebo
Serious adverse events · people with chronic gout
Allopurinol showed no clear difference in serious adverse events compared with placebo (moderate certainty).
1 finding from 1 review
- RR 1.93 [0.48, 7.8]2 studies · 453 participantsModerate
Intervention not reported
Serious adverse events · Adults with cancer pain
1 finding from 1 review
- Codeine, alone and with paracetamol (acetaminophen), for cancer pain 2014 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedVery low
Low‐pressure vs standard pressure pneumoperitoneum
Serious adverse events · patients with laparoscopic cholecystectomy.
It is very uncertain whether low pressure changes serious adverse events compared with standard pressure pneumoperitoneum (very low certainty).
1 finding from 1 review
- Low pressure versus standard pressure pneumoperitoneum in laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes onlyRR 3 [0.14, 65.9]7 studies · 394 participantsVery low
Local anaesthetic wound infiltration before incision vs end of surgery
Serious adverse events · patients with people undergoing laparoscopic cholecystectomy
1 finding from 1 review
- Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes onlyno estimate extracted1 study · 43 participantsVery low
Infiltration injection local anaesthetic vs no local anaesthetic wound infiltration
Serious adverse events · patients with people undergoing laparoscopic cholecystectomy.
It is very uncertain whether local anaesthetic wound infiltration changes serious adverse events compared with no local anaesthetic wound infiltration (very low certainty).
1 finding from 1 review
- Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes onlyRR 2 [0.19, 21.59]7 studies · 539 participantsVery low
Intervention not reported
Serious adverse events · people undergoing laparoscopic cholecystectomy.
1 finding from 1 review
- Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes onlyno estimate extracted1 study · 137 participantsVery low
Fewer‐than‐four ports vs four ports
Serious adverse events · people undergoing laparoscopic cholecystectomy.
It is very uncertain whether fewer‐than‐four ports changes serious adverse events compared with four ports (very low certainty).
1 finding from 1 review
- Fewer‐than‐four ports versus four ports for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes onlyRR 3.93 [0.86, 18.04]7 studies · 634 participantsVery low
Vedolizumab vs placebo
Serious adverse events · Patients with moderately to severely active ulcerative colitis
Vedolizumab showed no clear difference in serious adverse events compared with placebo (moderate certainty).
1 finding from 1 review
- Vedolizumab for induction and maintenance of remission in ulcerative colitis 2014 · Cochrane Headline outcomes onlyRR 1.01 [0.72, 1.42]3 studies · 1122 participantsModerate
Ascorbic acid vs placebo
Serious adverse events · people with fatigue in peripheral neuropathy
Ascorbic acid showed no clear difference in serious adverse events compared with placebo (moderate certainty).
1 finding from 1 review
- RR 0.7 [0.39, 1.27]2 studies · 450 participantsModerate
Amantadine vs placebo
Serious adverse events · people with fatigue in Guillain‐Barré syndrome
1 finding from 1 review
- no estimate extracted80 participantsGRADE not reported