Adverse events (moderate) · adults and children with cystic fibrosis (during acute exacerbations of lung disease)
It is very uncertain whether summary of findings: Inhaled antibiotics plus IV antibiotics changes adverse events moderate adverse events experienced during and after… compared with IV antibiotics only (very low certainty).
1 finding from 1 review
Discontinuation of medication due to adverse events · pre‐existing and new‐onset diabetes in kidney transplant recipients
1 finding from 1 review
Adverse events (not including serious adverse events): number of participants · patients with chronic obstructive pulmonary disease
Fixed‐dose combination aclidinium/formoterol leads to lower adverse events (not including serious adverse events): number of… compared with formoterol (high certainty).
1 finding from 1 review
Adverse events (not including serious adverse events): number of participants · patients with chronic obstructive pulmonary disease
Fixed‐dose combination aclidinium/formoterol showed no clear difference in adverse events (not including serious adverse events): number of… compared with placebo (moderate certainty).
1 finding from 1 review
Adverse events (not including serious adverse events): number of participants · patients with chronic obstructive pulmonary disease
Fixed‐dose combination aclidinium/formoterol showed no clear difference in adverse events (not including serious adverse events): number of… compared with aclidinium alone (moderate certainty).
1 finding from 1 review
Adverse effects. Specific: movement disorders ‐ parkinsonism · patients with schizophrenia
It is very uncertain whether chlorpromazine changes adverse effects/events: clinically important movement disorder… compared with piperacetazine (very low certainty).
1 finding from 1 review
Adverse events ‐ specific side effects attributed to oestrogen over 8 months' · women with PMS
It is very uncertain whether dose comparison: oestrogen 100 µg patch changes adverse events ‐ specific side effects attributed to oestrogen over… compared with 200 µg patch plus progestogen (very low certainty).
1 finding from 1 review
Adverse events ‐ incidents of unspecified severe adverse events ‐ medium term · Adults with co‐morbid PTSD and SMI
1 finding from 1 review
Adverse events ‐ incidents of unspecified severe adverse events ‐ medium term · Adults with co‐morbid PTSD and SMI
1 finding from 1 review
Adverse events: Movement disorder ‐ any extra pyramidal symptoms ‐ short term · patients with schizophrenia
RISPERIDONE DEPOT showed no clear difference in adverse events: Movement disorder ‐ any extra pyramidal symptoms ‐… compared with ORAL RISPERIDONE (moderate certainty).
1 finding from 1 review
Intervention not reported
Sensitivity analysis: proportion of participants experiencing adverse events. · people with chronic low back pain
The intervention showed no clear difference in sensitivity analysis: proportion of participants experiencing… (moderate certainty).
1 finding from 1 review
Adverse events ‐ death in past 12 months (RR > 1 denotes higher risk of death) · adult patients with alcohol dependence
It is very uncertain whether lay health worker‐led interventions changes adverse events ‐ death in past 12 months (RR > 1 denotes higher risk… compared with enhanced usual care (very low certainty).
1 finding from 1 review
Adverse events The timing of measurement was post‐intervention for all studies · people with multiple sclerosis
Exercise showed no clear difference in adverse events The timing of measurement was post‐intervention for… compared with control (post‐intervention) (low certainty).
1 finding from 1 review
Intervention not reported
Number of adverse events requiring discontinuation of treatment ‐ not reported · treating infections in people with neutropenia or neutrophil dysfunction
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Serious adverse events related to the use of physical restraints ‐ not measured · older people in all long‐term care settings
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events ‐ temporary or permanent discontinuation/hospitalisation at final · primary membranous nephropathy in adults with nephrotic syndrome
Immunosuppressive treatment probably leads to higher adverse events: temporary/permanent discontinuation or… compared with placebo/no treatment/non‐immunosuppressive supportive treatment (moderate certainty).
1 finding from 1 review
Adverse events (unexpected cardiac or respiratory arrest) – non‐randomised studies ( · adult on acute hospital wards at risk of clinical deterioration
2 findings from 1 review
AOR 0.94 [0.79, 1.13]
364094 participants
Low
no estimate extracted
Studies not reported
Very low
Number of participants with adverse events (epigastric pain, nausea, diarrhoea) · patients with the need for management of diverticulitis
5‐ASA showed no clear difference in number of participants with adverse events (epigastric pain, nausea,… compared with control (all trials) (moderate certainty).
1 finding from 1 review
Adverse events: hypertension · patients with the anaemia of end‐stage kidney disease undergoing dialysis
CERA showed no clear difference in numbers of adverse events due to hypertension: CERA every 2 weeks… compared with other ESA (high certainty).
1 finding from 1 review
Systemic adverse events: abnormal cortisol; end of treatment (1‐6 weeks) · children and adults, most with moderate to severe eczema
1 finding from 1 review