Cochrane · systematic review · CD012475

Interventions for preventing falls in people with multiple sclerosis

Hayes, S, Galvin, R, Kennedy, C, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
3
No studies
1
Included studies
NR
No studies 1 · 25%Ungraded 0 · 0%Very low 1 · 25%Low 2 · 50%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Exercise compared to control (post‐intervention) for preventing falls in people with multiple sclerosis

Population: people with multiple sclerosis (including people with relapsing‐remitting, secondary progressive or primary progressive types of MS), mean age: 53 years
4 questions
OutcomeEffectEvidenceStatus / GRADE
Falls rate Falls were measured using prospective daily diaries, prospective monthly calendars or retrospectively. Falls rate calculation= number of falls/number in group * (number of days/365) The timing of measurement was post‐intervention for al...
Exercise vs control (post‐intervention)
Rate ratio 0.68 [0.43, 1.06]5 studies · 399 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Number of fallers Falls were measured using prospective daily diaries, prospective monthly calendars or retrospectively The timing of measurement was post‐intervention for all studies
Exercise vs control (post‐intervention)
RR 0.85 [0.51, 1.43]5 studies · 355 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Adverse events The timing of measurement was post‐intervention for all studies
Exercise vs control (post‐intervention)
RR 1.25 [0.26, 6.03]3 studies · 97 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Quality of life
Exercise vs control (post‐intervention)
no estimate extractedNRNo studies