Cochrane · systematic review · CD011464
Psychological interventions for post‐traumatic stress disorder (PTSD) in people with severe mental illness
Sin, J, Spain, D, Furuta, M, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
SchizophreniaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
28
current version
GRADE rated
11
No studies
17
Included studies
NR
No studies 17 · 60.7%Ungraded 0 · 0%Very low 4 · 14.3%Low 7 · 25%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Individual TF‐CBT compared to waiting list/usual care for PTSD and severe mental illness
Population: Adults with co‐morbid PTSD and SMI
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
PTSD symptoms: Clinician‐rated PTSD symptom severity ‐ average endpoint CAPS total score (high = poor) ‐ short term (6 months) Individual TF‐CBT vs waiting list/usual care | no estimate extracted | 1 study · 13 participants | Low Downgraded: imprecision, indirectness |
Quality of life: 1. General quality of life ‐ average endpoint QLS total score (high = good) ‐ medium term Individual TF‐CBT vs waiting list/usual care | no estimate extracted | 1 study · 39 participants | Low Downgraded: imprecision, indirectness |
Symptoms of co‐morbid psychosis: 1. Overall mental state ‐ average endpoint BPRS total score (high = poor) ‐ medium term Individual TF‐CBT vs waiting list/usual care | no estimate extracted | 1 study · 9 participants | Low Downgraded: imprecision, indirectness |
Anxiety symptoms ‐ average endpoint BAI total score (high = poor) ‐ medium term (12 months) Individual TF‐CBT vs waiting list/usual care | no estimate extracted | 1 study · 9 participants | Very low Downgraded: imprecision, indirectness |
Depressive symptoms ‐ average endpoint BDI‐II total (high = poor) ‐ medium term (12 months) ‐ skewed data Individual TF‐CBT vs waiting list/usual care | no estimate extracted | 2 studies · 48 participants | Very low Downgraded: imprecision, indirectness |
Adverse events ‐ incidents of unspecified severe adverse events ‐ medium term Individual TF‐CBT vs waiting list/usual care | no estimate extracted | 1 study · 100 participants | Low Downgraded: imprecision |
Health economics Individual TF‐CBT vs waiting list/usual care | no estimate extracted | NR | No studies |
EMDR compared to waiting list/usual care for PTSD and severe mental illness
Population: Adults with co‐morbid PTSD and SMI
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
PTSD symptom severity: 1. Clinician‐rated severity ‐ average endpoint CAPS total score (high = poor) ‐ Medium term ‐ skewed data EMDR vs waiting list/usual care | no estimate extracted | 1 study · 83 participants | Very low Downgraded: imprecision |
Quality of life: 1. General quality of life EMDR vs waiting list/usual care | no estimate extracted | NR | No studies |
Symptoms of co‐morbid psychosis: 1. Overall mental state EMDR vs waiting list/usual care | no estimate extracted | NR | No studies |
Anxiety symptoms EMDR vs waiting list/usual care | no estimate extracted | NR | No studies |
Depressive symptoms EMDR vs waiting list/usual care | no estimate extracted | NR | No studies |
Adverse events ‐ incidents of unspecified severe adverse events ‐ medium term EMDR vs waiting list/usual care | no estimate extracted | 1 study · 102 participants | Low Downgraded: imprecision |
Health economics EMDR vs waiting list/usual care | no estimate extracted | NR | No studies |
Individual TF‐CBT compared to EMDR for PTSD and severe mental illness
Population: Adults with co‐morbid PTSD and SMI
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
PTSD symptom severity: 1. Clinician‐rated severity ‐ average endpoint CAPS total score (high = poor) ‐ Medium term ‐ skewed data Individual TF‐CBT vs EMDR | no estimate extracted | 1 study · 88 participants | Very low Downgraded: imprecision |
Quality of life: 1. General quality of life Individual TF‐CBT vs EMDR | no estimate extracted | NR | No studies |
Symptoms of co‐morbid psychosis: 1. Overall mental state Individual TF‐CBT vs EMDR | no estimate extracted | NR | No studies |
Anxiety symptoms Individual TF‐CBT vs EMDR | no estimate extracted | NR | No studies |
Depressive symptoms Individual TF‐CBT vs EMDR | no estimate extracted | NR | No studies |
Adverse events ‐ incidents of unspecified severe events ‐ medium term Individual TF‐CBT vs EMDR | no estimate extracted | NR | No studies |
Health economics Individual TF‐CBT vs EMDR | no estimate extracted | NR | No studies |
Individual TF‐CBT compared to Brief PTSD psychoeducation for PTSD and severe mental illness
Population: Adults with co‐morbid PTSD and SMI
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
PTSD symptom severity: 1. Clinician‐rated PTSD severity ‐ average endpoint CAPS total score (high = poor) ‐ Medium term Individual TF‐CBT vs Brief PTSD psychoeducation | no estimate extracted | 1 study · 52 participants | Low Downgraded: imprecision |
Quality of life: 1. General quality of life ‐ average endpoint QoLI total score (high = good) ‐ Long term Individual TF‐CBT vs Brief PTSD psychoeducation | no estimate extracted | 1 study · 49 participants | Low Downgraded: imprecision |
Symptoms of co‐morbid psychosis: 1. Overall mental state Individual TF‐CBT vs Brief PTSD psychoeducation | no estimate extracted | NR | No studies |
Anxiety symptoms Individual TF‐CBT vs Brief PTSD psychoeducation | no estimate extracted | NR | No studies |
Depressive symptoms Individual TF‐CBT vs Brief PTSD psychoeducation | no estimate extracted | NR | No studies |
Adverse events ‐ incidents of unspecified severe adverse events Individual TF‐CBT vs Brief PTSD psychoeducation | no estimate extracted | NR | No studies |
Health economics Individual TF‐CBT vs Brief PTSD psychoeducation | no estimate extracted | NR | No studies |