Cochrane · systematic review · CD012087
Non‐steroidal anti‐inflammatory drugs for chronic low back pain
Enthoven, WTM, Roelofs, PDDM, Deyo, RA, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
Back and NeckAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 50%Moderate 3 · 50%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
NSAIDs for people with chronic low back pain
Population: people with chronic low back pain
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Change in pain intensity from baseline 100 mm VAS | no estimate extracted | 6 studies · 1354 participants | Low Downgraded: risk of bias, publication bias |
Change in disability from baseline RDQ 0 to 24 | no estimate extracted | 4 studies · 1161 participants | Low Downgraded: risk of bias, publication bias |
Proportion of participants experiencing adverse events | RR 1.04 [0.92, 1.17] | 6 studies · 1354 participants | Low Downgraded: risk of bias, publication bias |
Sensitivity analysis: change in pain intensity from baseline 100 mm VAS | no estimate extracted | 3 studies · 728 participants | Moderate Downgraded: risk of bias |
Sensitivity analysis: change in disability from baseline RDQ 0 to 24 | no estimate extracted | 2 studies · 654 participants | Moderate Downgraded: risk of bias |
Sensitivity analysis: proportion of participants experiencing adverse events. | RR 0.93 [0.81, 1.07] | 3 studies · 728 participants | Moderate Downgraded: risk of bias |