Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

46 questions · 46 findings · 15 reviews · Pain, Palliative and Supportive Care

No studies found 6 · 13%GRADE not reported 0 · 0%Very low 12 · 26.1%Low 15 · 32.6%Moderate 10 · 21.7%High 3 · 6.5%

Intravenous ketorolac vs NSAIDs

Number of women requiring rescue medication · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries

It is very uncertain whether intravenous ketorolac changes number of participants using rescue medication over 4 or 6 hours… compared with another NSAID (very low certainty).

1 finding from 1 review

Intravenous ketorolac vs placebo

Use of rescue medication · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries

It is very uncertain whether intravenous ketorolac changes number of participants using rescue medication over 4 or 6 hours… compared with placebo (very low certainty).

1 finding from 1 review

Ketorolac vs placebo

Use of rescue medication · children with acute postoperative pain

It is very uncertain whether ketorolac changes participants using rescue medication in the PACU compared with placebo (very low certainty).

1 finding from 1 review

Intravenous diclofenac vs NSAIDs

Number of participants using rescue medication over 4 to 6 hours postinterventions · Adults (mean study ages 25 to 55 years) with acute postoperative pain after dental, mixed minor, abdominal, or orthopedic surgeries

It is very uncertain whether intravenous diclofenac changes number of participants using rescue medication over 4 to 6 hours… compared with another NSAID (very low certainty).

1 finding from 1 review

Intravenous diclofenac vs placebo

Number of participants using rescue medication over 4 to 6 hours postinterventions · Adults (mean study ages 25 to 55 years) with acute postoperative pain after dental, mixed minor, abdominal, or orthopedic surgeries

Intravenous diclofenac may leads to lower number of participants using rescue medication over 4 to 6 hours… compared with placebo (low certainty).

1 finding from 1 review