Question · asked by 1 review
Prophylactic dopamine antagonist antiemetic medications vs placebo: Adverse events
- Population
- adults receiving intravenous opioids
- Intervention
- Prophylactic dopamine antagonist antiemetic medications
- Comparison
- placebo
- Outcome
- Adverse events
Prophylactic dopamine antagonist antiemetic medications showed no clear difference in adverse events compared with placebo (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Prophylactic dopamine antagonist antiemetic medications vs placebo Adverse events · adults receiving intravenous opioids Prophylactic dopamine antagonist antiemetic medications showed no clear difference in adverse events compared with placebo (low certainty). Prophylactic antiemetics for adults receiving intravenous opioids in the acute care setting (2022) · Cochrane Headline outcomes only | RR 2.34 [0.47, 11.61] | 3 studies · 527 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Prophylactic antiemetics for adults receiving intravenous opioids in the acute care setting 2022 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.