Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

343 questions · 347 findings · 29 reviews · Eyes and Vision

No studies found 94 · 27.1%GRADE not reported 11 · 3.2%Very low 81 · 23.3%Low 110 · 31.7%Moderate 47 · 13.5%High 4 · 1.2%

Non‐pharmaceutical interventions vs control

Visual acuity · people with traumatic hyphema

Non‐pharmaceutical interventions showed no clear difference in short‐term visual acuity between 20/20 and 20/60 at end of… compared with control (low certainty).

2 findings from 1 review

Non‐pharmaceutical interventions vs control

Final visual acuity between 20/20 and 20/50; monocular vs binocular eye patching · people with traumatic hyphema

Non‐pharmaceutical interventions showed no clear difference in final visual acuity between 20/20 and 20/50; monocular vs binocular… compared with control (low certainty).

1 finding from 1 review

Non‐pharmaceutical interventions vs control

Risk of secondary hemorrhage; monocular versus binocular eye patching · people with traumatic hyphema

Non‐pharmaceutical interventions showed no clear difference in risk of secondary hemorrhage; monocular vs binocular eye patching compared with control (low certainty).

1 finding from 1 review

Non‐pharmaceutical interventions vs control

Risk of secondary hemorrhage; ambulatory treatment versus bed rest · people with traumatic hyphema

Non‐pharmaceutical interventions showed no clear difference in risk of secondary hemorrhage; ambulatory treatment vs bed rest compared with control (low certainty).

1 finding from 1 review

Phacoemulsification vs laser peripheral iridotomy

Proportion of participants requiring further IOP‐lowering interventions (additional surgery, medications, or both) (lower number of events is better) · Participants with acute primary angle closure after initial medical treatment to lower intraocular pressure

It is very uncertain whether phacoemulsification changes proportion of participants requiring further IOP‐lowering… compared with laser peripheral iridotomy (very low certainty).

1 finding from 1 review

Intervention not reported

Further surgical or laser interventions · adults with PACS or PAC, and previous PI

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Further surgical or laser interventions · adults with PAC or PACG, and previous PI
1 finding from 1 review

Oral antibiotics vs placebo

Economic costs and benefits of different interventions · adult participants with chronic blepharitis

The review found no eligible studies for this question.

1 finding from 1 review

Blue‐light filtering intraocular lenses (IOL) vs non blue‐light filtering IOL

Proportion of participants with adverse events with a probable causal link with the study interventions at six months · adults undergoing cataract surgery with IOL implantation

The review found no eligible studies for this question.

1 finding from 1 review

Other pharmaceutical agents vs placebo or control

Risk of secondary hemorrhage; conjugated estrogen · people with traumatic hyphema

Other pharmaceutical agents showed no clear difference in risk of secondary hemorrhage; conjugated estrogen compared with placebo or other control interventions (moderate certainty).

1 finding from 1 review

Other pharmaceutical agents vs placebo or control

Risk of secondary hemorrhage; cycloplegics · people with traumatic hyphema

It is very uncertain whether other pharmaceutical agents changes risk of secondary hemorrhage; cycloplegics compared with placebo or other control interventions (very low certainty).

1 finding from 1 review