Dental caries in children · Children (approx. 4-18 years)
Pooling studies that used BMI as a continuous variable showed no significant association between per-unit BMI and childhood dental caries (OR 1.01, 95% CI 0.99 to 1.03; I2=3.5%); ungraded.
3 findings from 1 review
Caries experience (mean DMFT) · Brazilian children in primary dentition (BMI classified by CDC 2000 growth charts)
Overweight may make little or no difference to caries experience (dmft) in the primary dentition of Brazilian children (very low certainty).
1 finding from 1 review
Caries experience (mean DMFT) · Brazilian children/adolescents in permanent dentition (BMI classified by CDC 2000 growth charts)
Overweight may make little or no difference to caries experience (DMFT) in the permanent dentition (very low certainty).
1 finding from 1 review
Caries experience (mean DMFT) · Brazilian children in primary dentition (BMI classified by CDC 2000 growth charts)
Obesity may make little or no difference to caries experience (dmft) in the primary dentition (very low certainty).
1 finding from 1 review
Untreated dental caries (d component), continuous · Brazilian children/adolescents (BMI classified by WHO 2007 Z-score)
Obesity may make little or no difference to untreated dental caries (low certainty).
1 finding from 1 review
Untreated dental caries (d component), continuous · Brazilian children/adolescents (BMI classified by WHO 2007 Z-score)
Overweight may make little or no difference to untreated dental caries (low certainty).
1 finding from 1 review
Caries experience (mean DMFT) · Brazilian children/adolescents in permanent dentition (BMI classified by CDC 2000 growth charts)
Normal-weight adolescents may have higher caries experience (DMFT) than obese peers in the permanent dentition, but the evidence is very uncertain (very low certainty).
1 finding from 1 review
Oral health-related quality of life · Indian children, adolescents and adults
One GOHAI study found no significant difference in OHRQoL by malocclusion status; ungraded.
2 findings from 1 review
Malocclusion and QoL (continuous, GOHAI): no significant difference in OHRQoL between individuals with and without malocclusion (Appukuttan 2016). Single study, not pooled.
1 study
GRADE not reported
Malocclusion and QoL (continuous, OHIP-14/ECOHIS/FIS): malocclusion had a significant negative influence on OHRQoL (Vinayagamoorthy 2020, Mary 2019). Not pooled.
2 studies
GRADE not reported
Oral health-related quality of life · Indian children and adults
Two studies found bruxers have poorer OHRQoL than non-bruxers; narrative, ungraded.
1 finding from 1 review
Bruxism and QoL (continuous, OHIP-14): bruxers have poorer OHRQoL than non-bruxers (Thetakala 2018, Suguna 2020). Two studies, 284 individuals; not pooled.
2 studies · 284 participants
GRADE not reported
Oral health-related quality of life · Indian adults and elderly (general, police, teachers, institutionalised)
No difference in OHRQoL was seen between groups for periodontal disease by LOA on OHIP-14/OIDP (pooled SMD -0.04, CI includes 0); ungraded.
2 findings from 1 review
SMD -0.04 [-2.01, 1.92]
4 studies · 3414 participants
Very low
Periodontal disease (LOA) and QoL (continuous, GOHAI): one study reported a significant negative impact (Rekhi 2016), one found no significant association (Marya 2020). Not pooled.
2 studies
GRADE not reported
Oral health-related quality of life · Indians
Continuous analyses (GOHAI, OHIP-14) of gingivitis and OHRQoL were inconsistent and mostly non-significant; ungraded.
1 finding from 1 review
Gingivitis and QoL (continuous): GOHAI - one study found poorer QoL (Appukuttan 2016, P<0.05), one no significant association (Marya 2020, P=0.08); OHIP-14 - no impact (Sreela 2020, P=0.0762). Not pooled.
3 studies
GRADE not reported
Oral health-related quality of life · Indian adults and elderly (general, police, teachers, institutionalised)
No difference in OHRQoL was seen between groups for periodontal disease by CPI on OHIP-14/OIDP (pooled SMD -0.18, CI includes 0); ungraded.
2 findings from 1 review
SMD -0.18 [-0.53, 0.18]
4 studies · 3064 participants
Very low
Periodontal disease (CPI) and QoL (continuous, GOHAI): CPI scores negatively correlated with QoL in one study (Rekhi 2016); no significant relation in another (Marya 2020, P>0.05). Not pooled.
2 studies
GRADE not reported
Oral health-related quality of life · Indians
Three studies using GOHAI found dental caries associated with poorer OHRQoL (P<0.05); narrative, ungraded.
2 findings from 1 review
Dental caries and QoL (GOHAI): all three studies (Appukuttan 2016, Rekhi 2018, Rekhi 2015) found decayed teeth associated with poorer QoL (P<0.05); not pooled.
3 studies
GRADE not reported
SMD 0.87 [0.34, 1.40]
6 studies · 4511 participants
Moderate
Oral health-related quality of life · Indian elderly
Continuous (GOHAI/WHOQoL) evidence on edentulism and OHRQoL was inconsistent across two studies; ungraded.
2 findings from 1 review
Edentulism and QoL (continuous, GOHAI/WHOQoL): one study reported edentulism negatively influenced QoL (Marina 2019), one found no effect (Appukuttan 2016). Not pooled.
2 studies
GRADE not reported
Edentulism and QoL (continuous, OHIP-14): no significant association between individuals with and without edentulism (Ajai 2020). Single study, not pooled.
1 study
GRADE not reported
Oral health-related quality of life · Indian children aged 3-5 years
In children aged 3-5 years, early childhood caries was significantly associated with poorer OHRQoL (narrative; 3 studies); ungraded.
1 finding from 1 review
Oral health-related quality of life · Indian children and young adults
Two studies found dental fluorosis significantly associated with poorer OHRQoL; narrative, ungraded.
1 finding from 1 review
Dental fluorosis and QoL (continuous, OIDP/CPQ11-14): a significant difference between individuals with and without fluorosis on OHRQoL (Nagarajappa 2015, Shyam 2020). Two studies, 3000 individuals; not pooled.
2 studies · 3000 participants
GRADE not reported
Oral health-related quality of life · Indian elderly
No significant difference in OHRQoL (GOHAI) was found for functional edentulism vs none (pooled SMD 0.31, CI includes 0); ungraded.
1 finding from 1 review
Oral health-related quality of life · Indian elderly and general-population adults
One study found prosthetic need significantly related to OHRQoL components on OHIP-14; ungraded.
2 findings from 1 review
Prosthetic need and QoL (continuous, OHIP-14): prosthetic need was significantly related to various components of OHRQoL (Joseph 2016). Single study, not pooled.
1 study
GRADE not reported
Prosthetic need and QoL (continuous, GOHAI): of three studies, one found no significant difference (Shetty 2013) and two proved the association (Pillai 2015, Rekhi 2018). Not pooled.
3 studies
GRADE not reported
All-cause mortality (ACM) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies
Each additional lost tooth was associated with a multivariable-adjusted HR of 1.02 (95% CI 1.01 to 1.03) for all-cause mortality (11 studies, I2=89%), statistically significant; GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).
3 findings from 1 review
Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies
Each additional lost tooth was associated with a multivariable-adjusted HR of 1.02 (95% CI 1.01 to 1.03) for ACVD-related events (13 studies, I2=75%), statistically significant; GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).
3 findings from 1 review