Findings

What do systematic reviews say?

2,922 questions · 3,118 findings · 513 reviews

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No studies found 574 · 18.4%GRADE not reported 372 · 11.9%Very low 723 · 23.2%Low 854 · 27.4%Moderate 489 · 15.7%High 106 · 3.4%

Intervention not reported

Pain Intensity immediate post‐treatment (3 weeks) · Patients with chronic non‐specific neck pain

1 finding from 1 review

Electrotherapy for neck pain 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 52 participants
Low

Strong opioids vs placebo

Mean pain intensity (Numeric Rating Scale 0–10) · adults with chronic low‐back pain

1 finding from 1 review

Opioids compared to placebo or other treatments for chronic low‐back pain 2013 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 1887 participants
Moderate

Paracervical vs placebo

Adverse events: hypotension · patients with cervical dilatation and uterine intervention

Paracervical probably leads to higher adverse effects ‐ Hypotension compared with placebo (moderate certainty).

1 finding from 1 review

Paracervical local anaesthesia for cervical dilatation and uterine intervention 2013 · Cochrane Headline outcomes only
RR 3.06 [1.21, 7.78]
2 studies · 171 participants
Moderate

Intervention not reported

Manual Muscle Testing score at 3 months Right and left shoulder abduction, elbow flexion and extension, finger abduction and extension, hip flexion, knee flexion and extension, foot dorsiflexion and plantarflexion assessed and graded 0 to 5 Medica... · people with amyotrophic lateral sclerosis or motor neuron disease

1 finding from 1 review

Therapeutic exercise for people with amyotrophic lateral sclerosis or motor neuron disease 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Moderate

Monitoring of contractions with internal tocodynamometry vs external tocodynamometry

Admission to neonatal intensive care unit

Monitoring of contractions with internal tocodynamometry showed no clear difference in admission to neonatal intensive care compared with external tocodynamometry (moderate certainty).

1 finding from 1 review

Internal versus external tocodynamometry during induced or augmented labour 2013 · Cochrane Headline outcomes only
RR 0.34 [0.07, 1.67]
2 studies · 489 participants
Moderate

Tacrolimus vs cyclosporin

Hypertension · lung transplant recipients

Tacrolimus may leads to lower arterial hypertension compared with cyclosporin (low certainty).

1 finding from 1 review

Tacrolimus versus cyclosporin as primary immunosuppression for lung transplant recipients 2013 · Cochrane Headline outcomes only
RR 0.67 [0.5, 0.89]
2 studies · 164 participants
Low

Fibrinogen concentrate vs any comparator

ICU length of stay (general intensive care patients) · bleeding patients or at risk of severe bleeding

1 finding from 1 review

Fibrinogen concentrate in bleeding patients 2013 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 112 participants
Very low

Morphine vs metamizole

Improvements in pain intensity as defined by the trialist (primary outcome) · participants with acute pancreatitis pain

Morphine showed no clear difference in improvements in pain intensity as defined by the trialist (primary… compared with metamizole (low certainty).

1 finding from 1 review

Opioids for acute pancreatitis pain 2013 · Cochrane Headline outcomes only
RR 0.5 [0.19, 1.33]
1 study · 16 participants
Low

Resistance training vs flexibility exercise

Strength Maximal isokinetic strength of nondominant knee extension measured in foot‐pounds8 · patients with fibromyalgia

1 finding from 1 review

Resistance exercise training for fibromyalgia 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 56 participants
Low

Resistance training vs control

Muscle strength · patients with fibromyalgia

1 finding from 1 review

Resistance exercise training for fibromyalgia 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 47 participants
Low

Glucosamine sulfate (oral) vs ibuprofen

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria

Glucosamine sulfate (oral) showed no clear difference in brief Pain Inventory (BPI) - pain intensity, change from baseline compared with ibuprofen (oral); GRADE not reported.

1 finding from 1 review

Interventions for managing temporomandibular joint osteoarthritis 2012 · Cochrane All outcomes
90 days
MD -2.69 [-7.38, 2.00]
1 study · 45 participants
GRADE not reported

Colchicine (0.5 mg three times per day) vs Clofazimine (100 mg daily for 30 days, then 100 mg every other day)

Complete remission, pain intensity, patient and physician evaluation · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

1 finding from 1 review

Systemic interventions for recurrent aphthous stomatitis (mouth ulcers) 2012 · Cochrane All outcomes
6 months
One trial at high risk of bias (de Abreu 2009) compared clofazimine (n=23) with colchicine (n=23). The number with no further aphthous episodes at 6 months was significantly greater in the clofazimine group than the…
1 study · 46 participants
GRADE not reported

Camel thorn (plant distillate) vs placebo

Pain intensity and lesion diameter · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

1 finding from 1 review

Systemic interventions for recurrent aphthous stomatitis (mouth ulcers) 2012 · Cochrane All outcomes
up to 14 days
The authors report lower pain and smaller lesions in the camel thorn group up to 10 days after referral; a statistically significant difference in pain intensity was also reported.
1 study · 93 participants
GRADE not reported

Intervention not reported

Pain Intensity ‐ short‐term · Patients with subacute/chronic mechanical neck pain

1 finding from 1 review

Massage for mechanical neck disorders 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 106 participants
Low

Intervention not reported

Pain Intensity: Short term · Patients with unknown duration of mechanical neck pain

1 finding from 1 review

Massage for mechanical neck disorders 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 180 participants
Low

Intervention not reported

Pain Intensity: short‐term · Patients with subacute/chronic mechanical neck pain

1 finding from 1 review

Massage for mechanical neck disorders 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 108 participants
Low

Intervention not reported

Length of stay on the intensive care unit (days) · Adult patients with SIRS or sepsis

1 finding from 1 review

N‐acetylcysteine for sepsis and systemic inflammatory response in adults 2012 · Cochrane Headline outcomes only
no estimate extracted
19 studies · 1309 participants
Moderate

Black cohosh vs placebo

Vasomotor symptoms: hot flush intensity · patients with menopausal symptoms

1 finding from 1 review

Black cohosh (Cimicifuga spp.) for menopausal symptoms 2012 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 214 participants
Moderate

Intervention not reported

Primary Outcome: Hypotension · Adults (over 18 years) with requirement for an ERCP procedure with diagnostic intent

1 finding from 1 review

Sedative techniques for endoscopic retrograde cholangiopancreatography 2012 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 510 participants
Moderate

Postoperative feeding via nasojejunal tube vs no postoperative parental nutrition (conventional intravenous electrolyte solution)

Intensive care unit length of stay after liver transplantation [hours] · adult patients after liver transplantation.

1 finding from 1 review

Nutritional interventions for liver‐transplanted patients 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
Very low