Cochrane · systematic review · CD005056
Paracervical local anaesthesia for cervical dilatation and uterine intervention
Tangsiriwatthana, T, Sangkomkamhang, US, Lumbiganon, P, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
21
current version
GRADE rated
19
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 2 · 9.5%Very low 1 · 4.8%Low 8 · 38.1%Moderate 5 · 23.8%High 5 · 23.8%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Paracervical versus placebo for cervical dilatation and uterine intervention
Population: patients with cervical dilatation and uterine intervention
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain dilating cervix Paracervical vs placebo | no estimate extracted | 4 studies · 381 participants | High |
Pain during uterine intervention ‐ Risk of any pain Paracervical vs placebo | RR 0.85 [0.54, 1.34] | 2 studies · 242 participants | Low Downgraded: inconsistency |
Pain during uterine intervention ‐ Risk of severe pain Paracervical vs placebo | RR 0.16 [0.04, 0.74] | 2 studies · 242 participants | Moderate Downgraded: risk of bias |
Postoperative pain ‐ Immediately after the procedure Paracervical vs placebo | no estimate extracted | 3 studies · 223 participants | Low Downgraded: risk of bias, inconsistency |
Adverse effects ‐ Nausea and vomiting Paracervical vs placebo | RR 0.24 [0.02, 2.8] | 3 studies · 429 participants | Moderate Downgraded: risk of bias, inconsistency |
Adverse effects ‐ Sweating Paracervical vs placebo | RR 1.08 [0.7, 1.67] | 1 study · 142 participants | Moderate Downgraded: risk of bias, inconsistency |
Adverse effects ‐ Hypotension Paracervical vs placebo | RR 3.06 [1.21, 7.78] | 2 studies · 171 participants | Moderate Downgraded: risk of bias, inconsistency |
Paracervical versus no anaesthesia for cervical dilatation and uterine intervention
Population: patients with cervical dilatation and uterine intervention
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain during the procedure Paracervical vs no anaesthesia | OR 0.99 [0.52, 1.86] | 1 study · 215 participants | High |
Postoperative pain at different times ‐ Immediately after the procedure Paracervical vs no anaesthesia | no estimate extracted | 2 studies · 273 participants | High |
Postoperative pain at different times ‐ 5 minutes after the procedure Paracervical vs no anaesthesia | no estimate extracted | 1 study · 58 participants | Ungraded |
Postoperative pain at different times ‐ 10 minutes after the procedure Paracervical vs no anaesthesia | no estimate extracted | 1 study · 58 participants | Ungraded |
Paracervical block versus other regional anaesthesia for cervical dilatation and uterine intervention
Population: patients with cervical dilatation and uterine intervention
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain during the procedure Paracervical block vs other regional anaesthesia | OR 1.41 [0.68, 2.91] | 1 study · 120 participants | Moderate Downgraded: risk of bias |
Pain during cervical dilatation Paracervical block vs other regional anaesthesia | no estimate extracted | 2 studies · 163 participants | Low Downgraded: inconsistency |
Pain during uterine intervention: continuous Paracervical block vs other regional anaesthesia | no estimate extracted | 3 studies · 271 participants | Very low Downgraded: imprecision, inconsistency |
Postoperative pain at different time: continuous Paracervical block vs other regional anaesthesia | no estimate extracted | 2 studies · 307 participants | High |
Adverse effects Paracervical block vs other regional anaesthesia | no estimate extracted | 1 study · 55 participants | Low Downgraded: risk of bias |
Paracervical versus systemic analgesia for cervical dilatation and uterine intervention
Population: patients with cervical dilatation and uterine intervention
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain during uterine intervention Paracervical vs systemic analgesia | no estimate extracted | 3 studies · 402 participants | Low Downgraded: risk of bias |
Postoperative pain Paracervical vs systemic analgesia | no estimate extracted | 2 studies · 984 participants | High |
Requirement for postoperative analgesics Paracervical vs systemic analgesia | no estimate extracted | 1 study · 166 participants | Low Downgraded: risk of bias |
Adverse effects Paracervical vs systemic analgesia | no estimate extracted | 3 studies · 571 participants | Low Downgraded: risk of bias |
Patient satisfaction Paracervical vs systemic analgesia | no estimate extracted | 1 study · 166 participants | Low Downgraded: risk of bias |