Cochrane · systematic review · CD005229
Therapeutic exercise for people with amyotrophic lateral sclerosis or motor neuron disease
Dal Bello‐Haas, V, Florence, JM · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
NeuromuscularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 14.3%Very low 0 · 0%Low 2 · 28.6%Moderate 4 · 57.1%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Exercise for people with amyotrophic lateral sclerosis or motor neuron disease
Population: people with amyotrophic lateral sclerosis or motor neuron disease
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
ALS Functional Rating Scale (ALSFRS) score at 3 months Scale from: 0 to 40 (higher is better). | no estimate extracted | 2 studies · 43 participants | Low Downgraded: risk of bias, imprecision |
Short‐Form‐36 Health Survey (SF‐36) score at 3 months Scale from: 0 to 100 (higher is better). | no estimate extracted | 1 study · 18 participants | Moderate Downgraded: risk of bias |
Fatigue Severity Scale score at 3 months Scale from: 0 to 63 (lower is better). | no estimate extracted | 2 studies · 43 participants | Low Downgraded: risk of bias, imprecision |
Manual Muscle Testing score at 3 months Right and left shoulder abduction, elbow flexion and extension, finger abduction and extension, hip flexion, knee flexion and extension, foot dorsiflexion and plantarflexion assessed and graded 0 to 5 Medica... | no estimate extracted | 1 study · 18 participants | Moderate Downgraded: risk of bias |
Upper extremity maximum voluntary isometric contraction score at 3 months Quantitative Muscle Assessment (QMA) system. Data were normalized, summed and averaged to yield an U/E megascore (higher is better). | no estimate extracted | 1 study · 22 participants | Moderate |
Lower extremity maximum voluntary isometric contraction score at 3 months Quantitative Muscle Assessment (QMA) system. Data were normalized, summed and averaged to yield a L/E megascore (higher is better). | no estimate extracted | 1 study · 20 participants | Moderate |
Adverse effects related to the intervention | no estimate extracted | 2 studies · 43 participants | Ungraded |