Findings

What do systematic reviews say?

3,097 questions · 3,266 findings · 631 reviews

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No studies found 430 · 13.2%GRADE not reported 193 · 5.9%Very low 995 · 30.5%Low 904 · 27.7%Moderate 591 · 18.1%High 153 · 4.7%

Intervention not reported

Disability (measured by the Glasgow Outcome Scale; higher score is better) · adults presenting with elevated intracranial pressure secondary to a traumatic brain injury

1 finding from 1 review

Indomethacin for intracranial hypertension secondary to severe traumatic brain injury in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

EMLA vs placebo

Pain during abdominal entry (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia

1 finding from 1 review

Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Intraperitoneal lidocaine instillation vs IM morphine

Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia

1 finding from 1 review

Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs placebo

Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia

1 finding from 1 review

Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs lidocaine intraperitoneal instillation alone

Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia

1 finding from 1 review

Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs IM morphine

Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia

1 finding from 1 review

Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Lidocaine instillation vs placebo

Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia

1 finding from 1 review

Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Intramuscular morphine vs placebo

Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia

1 finding from 1 review

Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

ECT plus standard care vs antipsychotics plus standard care

Mental state · people with treatment‐resistant schizophrenia

1 finding from 1 review

Electroconvulsive therapy for treatment‐resistant schizophrenia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 162 participants
Very low

ECT plus standard care vs usual care

Mental state · people with treatment‐resistant schizophrenia

1 finding from 1 review

Electroconvulsive therapy for treatment‐resistant schizophrenia 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 345 participants
Low

ECT plus standard care vs usual care

General functioning: Average endpoint general functioning score (clinically improved) (no data) · people with treatment‐resistant schizophrenia

1 finding from 1 review

Electroconvulsive therapy for treatment‐resistant schizophrenia 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 97 participants
Very low

ECT alone vs antipsychotics

Mental state · people with treatment‐resistant schizophrenia

1 finding from 1 review

Electroconvulsive therapy for treatment‐resistant schizophrenia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Very low

ECT alone vs antipsychotics

General functioning: Average endpoint general functioning score (clinically improved) (no data) · people with treatment‐resistant schizophrenia

1 finding from 1 review

Electroconvulsive therapy for treatment‐resistant schizophrenia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Very low

ECT plus standard care vs sham‐ECT plus standard care

Mental state · people with treatment‐resistant schizophrenia

1 finding from 1 review

Electroconvulsive therapy for treatment‐resistant schizophrenia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 25 participants
Very low

Robotic‐assisted laparoscopic vs open radical cystectomy

Quality of life (higher scores indicate better quality of life) · bladder cancer in adults

1 finding from 1 review

Robotic versus open radical cystectomy for bladder cancer in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 270 participants
Low

Aspirin plus antipsychotics vs placebo/no adjunctive treatment + antipsychotics

Clinical response: mean score/change in mental state: mean PANSS total score (high = poor) · patients with schizophrenia

1 finding from 1 review

Acetylsalicylic acid (aspirin) for schizophrenia 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 130 participants
Very low

Aerobic exercise and strength training vs usual care

Change from baseline in 6MWT (metres) · children and adults with SMA type 3

1 finding from 1 review

Physical exercise training for type 3 spinal muscular atrophy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 12 participants
Very low

Supplemental IV crystalloid vs control IV crystalloid volume

Risk of suffering a serious adverse event, reported dichotomously as the occurrence of any of: admission to high‐dependency unit, postoperative cardiac or respiratory complication, or death · participants aged 6 months or older undergoing surgical procedures under general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Supplemental perioperative intravenous crystalloids for postoperative nausea and vomiting 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Omega‐3 vs placebo

Mental state: psychotic symptoms Average total score (PANSS, higher score = worse, scale from 30‐210) Long‐term (up to 7 years) · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 81 participants
Low

Group B antipsychotic drugs: olanzapine + supportive intervention vs placebo or supportive treatment

Global effect: 1a. Medium‐term ‐ Average end point score on various outcomes ‐ CGI‐severity (low = favourable) ( · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Very low