Cochrane · systematic review · CD011807
Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation
Werawatakul, Y, Sothornwit, J, Laopaiboon, M, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
Fertility RegulationAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
21
current version
GRADE rated
21
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 7 · 33.3%Low 14 · 66.7%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
EMLA cream compared to placebo for pain during abdominal entry
Population: women undergoing PPTL under local anaesthesia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain during abdominal entry (NRS; higher = more pain) EMLA cream vs placebo | no estimate extracted | NR | Low Downgraded: risk of bias |
Adverse events within 48 hours post operation EMLA cream vs placebo | no estimate extracted | NR | Very low Downgraded: risk of bias |
Number of women requiring rescue medication EMLA cream vs placebo | RR 0.36 [0.25, 0.53] | NR | Low Downgraded: risk of bias |
Lidocaine instillation compared to placebo for intra‐operative intraperitoneal pain relief
Population: women undergoing PPTL under local anaesthesia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intraperitoneal pain (NRS; higher = more pain) Lidocaine instillation vs placebo | no estimate extracted | NR | Low Downgraded: risk of bias |
Adverse events within 48 hours post operation Lidocaine instillation vs placebo | RR 1.04 [0.4, 2.69] | NR | Very low Downgraded: risk of bias |
Number of women requiring rescue medication Lidocaine instillation vs placebo | RR 0.27 [0.17, 0.44] | NR | Low Downgraded: risk of bias |
Intramuscular morphine compared to placebo for intra‐operative intraperitoneal pain relief
Population: women undergoing PPTL under local anaesthesia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intraperitoneal pain (NRS; higher = more pain) Intramuscular morphine vs placebo | no estimate extracted | NR | Low Downgraded: risk of bias |
Adverse events within 48 hours post operation Intramuscular morphine vs placebo | no estimate extracted | NR | Very low Downgraded: risk of bias |
Number of women requiring rescue medication Intramuscular morphine vs placebo | RR 1 [0.81, 1.23] | NR | Low Downgraded: risk of bias |
Intraperitoneal lidocaine instillation compared to intramuscular morphine for intra‐operative intraperitoneal pain relief
Population: women undergoing PPTL under local anaesthesia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intraperitoneal pain (NRS; higher = more pain) Intraperitoneal lidocaine instillation vs intramuscular morphine | no estimate extracted | NR | Low Downgraded: risk of bias |
Adverse events within 48 hours post operation Intraperitoneal lidocaine instillation vs intramuscular morphine | no estimate extracted | NR | Very low Downgraded: risk of bias |
Number of women requiring rescue medication Intraperitoneal lidocaine instillation vs intramuscular morphine | RR 0.22 [0.09, 0.54] | NR | Low Downgraded: risk of bias |
Combination of intraperitoneal lidocaine instillation and intramuscular morphine administration compared to placebo for intra‐operative intraperitoneal pain relief
Population: women undergoing PPTL under local anaesthesia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intraperitoneal pain (NRS; higher = more pain) Combination of intraperitoneal lidocaine instillation and intramuscular morphine administration vs placebo | no estimate extracted | NR | Low Downgraded: risk of bias |
Adverse events within 48 hours post operation Combination of intraperitoneal lidocaine instillation and intramuscular morphine administration vs placebo | no estimate extracted | NR | Very low Downgraded: risk of bias |
Number of women requiring rescue medication Combination of intraperitoneal lidocaine instillation and intramuscular morphine administration vs placebo | RR 0.11 [0.03, 0.42] | NR | Low Downgraded: risk of bias |
Combination of lidocaine intraperitoneal instillation plus intramuscular morphine compared to lidocaine intraperitoneal instillation alone for intra‐operative intraperitoneal pain relief
Population: women undergoing PPTL under local anaesthesia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intraperitoneal pain (NRS; higher = more pain) Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs lidocaine intraperitoneal instillation alone | no estimate extracted | NR | Low Downgraded: risk of bias |
Adverse events within 48 hours post operation Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs lidocaine intraperitoneal instillation alone | no estimate extracted | NR | Very low Downgraded: risk of bias |
Number of women requiring rescue medication Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs lidocaine intraperitoneal instillation alone | RR 0.5 [0.1, 2.43] | NR | Low Downgraded: risk of bias |
Combination of lidocaine intraperitoneal instillation plus intramuscular morphine compared to intramuscular morphine alone for intra‐operative intraperitoneal pain relief
Population: women undergoing postpartum mini‐laparotomy tubal ligation (PPTL) under local anaesthesia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intraperitoneal pain (NRS; higher = more pain) Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs intramuscular morphine alone | no estimate extracted | NR | Low Downgraded: risk of bias |
Adverse events within 48 hours post operation Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs intramuscular morphine alone | no estimate extracted | NR | Very low Downgraded: risk of bias |
Number of women requiring rescue medication Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs intramuscular morphine alone | RR 0.11 [0.03, 0.42] | NR | Low Downgraded: risk of bias |