Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,584 questions · 3,695 findings · 567 reviews

No studies found 784 · 21.2%GRADE not reported 308 · 8.3%Very low 1,036 · 28%Low 971 · 26.3%Moderate 440 · 11.9%High 156 · 4.2%

Interventionist care vs expectant care

Intraventricular haemorrhage or hypoxic ischaemic encephalopathy · women with severe pre‐eclampsia between 24 and 34 weeks' gestation

Interventionist care probably leads to higher intraventricular haemorrhage or hypoxic ischaemic encephalopathy compared with expectant (delayed delivery) care (moderate certainty).

1 finding from 1 review

Beta‐blockers vs control—non‐cardiac surgery

Ventricular arrhythmias—non‐cardiac surgery ECG · patients with conditions requiring non‐cardiac surgery

Beta‐blocker showed no clear difference in ventricular arrhythmias—non‐cardiac surgery ECG compared with control—non‐cardiac surgery (moderate certainty).

1 finding from 1 review

Beta‐blockers vs control—non‐cardiac surgery

All supraventricular arrhythmias—non‐cardiac surgery ECG · patients with conditions requiring non‐cardiac surgery

Beta‐blocker leads to lower all supraventricular arrhythmias—non‐cardiac surgery ECG compared with control—non‐cardiac surgery (high certainty).

1 finding from 1 review

Beta‐blockers vs control—cardiac surgery

Ventricular arrhythmias—cardiac surgery ECG · patients with coronary heart disease and/or valvular heart disease

Beta‐blocker probably leads to lower ventricular arrhythmias—cardiac surgery ECG compared with control—cardiac surgery (moderate certainty).

1 finding from 1 review

Beta‐blockers vs control—cardiac surgery

All supraventricular arrhythmias—cardiac surgery ECG · patients with coronary heart disease and/or valvular heart disease

Beta‐blocker leads to lower all supraventricular arrhythmias—cardiac surgery ECG compared with control—cardiac surgery (high certainty).

1 finding from 1 review

Desipramine (antidepressant) vs placebo

ADHD symptom‐related behavior Measured by standardized rating scales: Child Behaviour Checklist, Gordon Diagnostic System, Clinical Evaluation of Language Function, Matching Familial Figures Test, Porteus Maze Test, Restricted Academic Test, ADHD ... · children with ADHD and comorbid tic disorders
1 finding from 1 review

tDCS vs sham

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults with chronic pain

It is very uncertain whether transcranial direct current stimulation (tDCS) changes pain intensity (0 to < 1 week postintervention) measured using… compared with sham (very low certainty).

1 finding from 1 review

Higher dose vitamin K vs lower dose vitamin K

Intraventricular hemorrhage > Grade II: 0.2 mg IM versus 0.5 mg IM · preterm infants

Higher dose vitamin K showed no clear difference in intraventricular hemorrhage > Grade II: 0.2 mg IM versus 0.5 mg IM compared with lower dose vitamin K (low certainty).

1 finding from 1 review

Intramuscular vitamin K vs intravenous vitamin K

Intraventricular hemorrhage > Grade II: 0.2 mg IV versus 0.2 mg IM · preterm infants

Intramuscular vitamin K showed no clear difference in intraventricular hemorrhage > Grade II: 0.2 mg IV versus 0.2 mg IM compared with intravenous vitamin K (low certainty).

1 finding from 1 review

Intramuscular vitamin K vs intravenous vitamin K

Intraventricular hemorrhage > Grade II: 0.2 mg IV versus 0.5 mg IM · preterm infants

Intramuscular vitamin K showed no clear difference in intraventricular hemorrhage > Grade II: 0.2 mg IV versus 0.5 mg IM compared with intravenous vitamin K (low certainty).

1 finding from 1 review

Intervention not reported

Adverse effects during treatment Intervention: Hyperbaric chamber/ 160 millibars versus supplementary oxygen · people suffering from high altitude illness
1 finding from 1 review

Lower vs higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm infants at birth

Severe intraventricular haemorrhage · preterm infants

Lower showed no clear difference in severe intraventricular haemorrhage (grade 3 or 4) compared with higher oxygen concentrations titrated to target oxygen saturations… (low certainty).

1 finding from 1 review