Cochrane · systematic review · CD003106
Interventionist versus expectant care for severe pre‐eclampsia between 24 and 34 weeks' gestation
Churchill, D, Duley, L, Thornton, JG, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 2 · 28.6%Low 3 · 42.9%Moderate 1 · 14.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Interventionist care compared to expectant (delayed delivery) care for severe pre‐eclampsia for severe pre‐eclampsia between 24 and 34 weeks' gestation
Population: women with severe pre‐eclampsia between 24 and 34 weeks' gestation
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Maternal death Interventionist care vs expectant (delayed delivery) care | no estimate extracted | 2 studies · 320 participants | Low Downgraded: risk of bias |
Eclampsia Interventionist care vs expectant (delayed delivery) care | RR 0.98 [0.06, 15.58] | 2 studies · 359 participants | Very low Downgraded: risk of bias, imprecision |
Stroke (brain damage) Interventionist care vs expectant (delayed delivery) care | no estimate extracted | NR | No studies |
HELLP syndrome Interventionist care vs expectant (delayed delivery) care | RR 1.09 [0.62, 1.91] | 2 studies · 359 participants | Low Downgraded: risk of bias, imprecision |
Pulmonary oedema Interventionist care vs expectant (delayed delivery) care | RR 0.45 [0.07, 3] | 3 studies · 415 participants | Very low Downgraded: risk of bias, imprecision |
Perinatal mortality or perinatal death Interventionist care vs expectant (delayed delivery) care | RR 1.11 [0.62, 1.99] | 3 studies · 343 participants | Low Downgraded: risk of bias, imprecision |
Intraventricular haemorrhage or hypoxic ischaemic encephalopathy Interventionist care vs expectant (delayed delivery) care | RR 1.94 [1.15, 3.29] | 2 studies · 537 participants | Moderate Downgraded: risk of bias, imprecision |