Cochrane · systematic review · CD009567
Interventions for treating acute high altitude illness
Simancas‐Racines, D, Arevalo‐Rodriguez, I, Osorio, D, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
Emergency and Critical CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
9
current version
GRADE rated
5
No studies
4
Included studies
NR
No studies 4 · 44.4%Ungraded 0 · 0%Very low 0 · 0%Low 5 · 55.6%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Non‐pharmacological interventions for treating acute high altitude illness
Population: people suffering from high altitude illness
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Outcomes and intervention | no estimate extracted | NR | No studies |
All‐cause mortality | no estimate extracted | NR | No studies |
Complete relief of AMS symptoms | no estimate extracted | NR | No studies |
Reduction in symptom score severity at 12 hours (Clinical score: ranged from 0 to 11 (worse)) Intervention: Simulated descent of 193 millibars versus 20 millibars | no estimate extracted | 1 study · 64 participants | Low Downgraded: risk of bias, imprecision |
Adverse effects during treatment Intervention: Hyperbaric chamber/ 160 millibars versus supplementary oxygen | no estimate extracted | 1 study · 29 participants | Low Downgraded: risk of bias, imprecision |
Pharmacological interventions for treating acute high altitude illness
Population: people suffering from high altitude illness
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality | no estimate extracted | NR | No studies |
Complete relief of AMS symptoms (12 to 16 hours after treatment) Scale used: Acute Mountain Sickness score (ranged from 0 to 9 (worse)) | no estimate extracted | 1 study · 35 participants | Low Downgraded: risk of bias |
Reduction in symptom score severity Time of measurement: 1 to 48 hours after treatment, end of treatment Scale of measurement: Self‐administered AMS questionnaires (ranged from 0 to 90 (worse)), AMS Symptom Questionnaire (ranged from 0 to 22 (wors... | Mean Difference 1.15 | 2 studies · 25 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Adverse effects Time of measurement: 1 to 48 hours after treatment, end of treatment Scale of measurement:not stated | no estimate extracted | 1 study · 25 participants | Low Downgraded: risk of bias, imprecision, inconsistency |