Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,288 questions · 3,354 findings · 516 reviews · Headline outcomes only

No studies found 720 · 21.5%GRADE not reported 164 · 4.9%Very low 950 · 28.3%Low 932 · 27.8%Moderate 434 · 12.9%High 154 · 4.6%

Amnioinfusion vs no amnioinfusion

Perinatal death or severe morbidity · pregnant women with confirmed or suspected chorioamnionitis

The review found no eligible studies for this question.

1 finding from 1 review

CHLORPROMAZINE vs RESERPINE

Mental state: Not improved (paranoid distortion) Multidimentional Scale for Rating Psychiatric Patients (short term) · patients with schizophrenia

It is very uncertain whether CHLORPROMAZINE changes mental state: Not improved (paranoid distortion) Multidimentional… compared with RESERPINE (very low certainty).

1 finding from 1 review

Rescue high‐frequency jet ventilation vs conventional ventilation

Severe intraventricular haemorrhage · preterm infants with severe pulmonary dysfunction

Rescue high‐frequency jet ventilation showed no clear difference in severe intraventricular haemorrhage (grades 3 and 4) compared with conventional ventilation (low certainty).

1 finding from 1 review

Vitamin E vs placebo, no placebo or other supplements

Intrauterine growth restriction · pregnant women receiving vitamin E supplementation or control, living in areas where there is either inadequate dietary intake of vitamin…

Any vitamin E supplementation showed no clear difference in intrauterine growth restriction (various definitions) compared with placebo, no placebo or other supplements (high certainty).

1 finding from 1 review

Intervention not reported

Intrauterine growth restriction · All pregnant women receiving either vitamin C supplementation or control either in areas where there is inadequate dietary intake or where…

The intervention showed no clear difference in intrauterine growth restriction (high certainty).

1 finding from 1 review

Intervention not reported

Generic waiting list · patients needing elective specialist ambulatory visit or surgery

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Neuropsychiatric symptoms Measured using NPI. Severity of symptoms is measured on a scale of 0‐144. A higher score indicates worse symptoms · people with dementia
1 finding from 1 review

Lidocaine vs disopyramide

Ventricular fibrillation · patients with myocardial infarction

It is very uncertain whether lidocaine changes ventricular fibrillation compared with disopyramide (very low certainty).

1 finding from 1 review

Lidocaine vs disopyramide

Adverse events (AEs; adverse drug reaction): cardiac blocks (high‐degree atrioventricular block and bundle) · patients with myocardial infarction

It is very uncertain whether lidocaine changes adverse events (AEs; adverse drug reaction): cardiac blocks… compared with disopyramide (very low certainty).

1 finding from 1 review

Lidocaine vs mexiletine

Ventricular fibrillation · patients with myocardial infarction

It is very uncertain whether lidocaine changes ventricular fibrillation compared with mexiletine (very low certainty).

1 finding from 1 review