Search review questions

Caries experience (mean DMFS) · European adolescents aged 12–19 years

Contribution to total daily fluoride intake · Children · High fluoride in water (0.78-1.5 mg/L)

Mucocele · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point)

Adverse events · Children with sound primary molars, aged 2-4 years (municipal dental clinics or hospital paediatric clinics, Denmark)

Secondary caries · Patients with permanent dentition in need of restorations · 1 year, All types of cavities

Adverse events · Children who were regular dental attenders with caries-free first or second primary molars (public health service…

Immediate bond strength (MPa) · Glass-ionomer cement bonded to caries-affected dentin (in vitro) · Immediate bond strength, Caries-affected dentin (with rinsing step)

Immediate bond strength (MPa) · Glass-ionomer cement bonded to dentin (in vitro), sound or caries-affected · Immediate bond strength, Overall (all dentin conditions and rinsing protocols)

Treatment failure (annual failure rate) · Children with carious primary teeth treated by atraumatic restorative treatment (hand-instrument caries removal), no… · 12-48 months, Restorative technique (ART)

Caries severity (mean DMFT) · 12-year-old children (permanent dentition) in Africa · Data collection period: >2015

Caries experience at the surface level (dmfs/defs) · Children (mean age newborn to ~5.2 years) and their parents/carers

Rate of complications and side effects of the intervention · People treated with oral bisphosphonates undergoing dental extractions (at risk of MRONJ)

Alpha diversity (Shannon) · Children providing oral (saliva/supragingival plaque) 16S rRNA microbiome samples · Children

Sensitivity for detecting enamel caries · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies) · Analysis 2: network meta-analysis (all studies evaluating >=2 index tests)

Dentinal caries in permanent (newly erupted) teeth · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of… · 7-year follow-up, Dentinal caries in primary dentition

Discrimination of caries vs health (random forest ROC-AUC) · Individuals providing oral (saliva/supragingival plaque) 16S rRNA microbiome samples; 2016 samples from 19 studies…

Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them · assistant level

Retention of sealant (complete or partial retention) · Children with caries-free primary first molars (with or without caries on other teeth), aged 1-5 years (paediatric… · 6-30 months

Discomfort during treatment · Children (3-10 years) with dentine caries in primary molars · During treatment

Restoration failure · Children with carious primary teeth · 3 years, Class II

Treatment failure (annual failure rate) · Children with carious primary molars treated by pulpotomy (vital pulp therapy) · 2 years, PMC arm

Mucocele prevalence · Children and adolescents (<18 years) living with HIV (CLWH)

Restoration failure · Children with carious primary teeth · 1 year, ART; Class I and II

Mortality or serious adverse events requiring hospitalisation · Adults or children at increased risk of bacterial endocarditis (pre-existing cardiac condition) undergoing an invasive…

Dental caries detection accuracy · Dental images of human beings · Zanella-Calzada et al., 2018; ANN

Pain at two weeks (postobturation) · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without… · Two weeks postobturation

Caries prevalence · 12-year-old children (permanent dentition) in Africa

Relative abundance of Veillonella spp. · Children with early childhood caries (ECC) and caries-free children · Overall (all sample types)

Restoration failure · Children with carious primary teeth · 2 years, ART; Class I and II

Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them · assistant level

Secondary caries (caries around restorations), all cavity types · Patients with permanent dentition in need of restorations (all cavity types: Black's Class I, II, V, and non-carious… · 3 years

Healing of MRONJ · People with established (manifest) MRONJ · 1 year

Early childhood caries (ECC) - association at lead SNP rs1044956 (7:24854765; nearest gene(s) OSBPL3, NPVF) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), rs1044956 (7:24854765); effect/non-effect allele A/G; MAF 0.49; direction across 5 cohorts +++++

Reduction in level of contamination by particles <=5 um (droplet nuclei) at >=2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them · droplet nuclei; aerobic cultures (9 feet behind patient)

Caries prevalence · European adolescents aged 12–19 years · Publication year: ≥ 2010

Caries prevalence · 12-year-old children (permanent dentition) in Africa · Setting: Rural

Food intake · Children and adolescents aged 0-19 years · Immediate/short-term (post-exposure), Nonrandomized studies

Oral candidiasis prevalence · Children and adolescents (<18 years) living with HIV (CLWH) · cART

Dental caries measured by DMFT scores · Primary school children (aged 3-16 years) attending primary school in low- and middle-income countries (LMICs) · Post-intervention; follow-up varied across studies (interventions ranged from <2 years to >=2 years and longer), Age 8-15 years

Retention of sealant (complete or partial retention) · Children with sound primary molars, aged 2-4 years (municipal dental clinics or hospital paediatric clinics, Denmark) · 24-36 months

Caries experience - % with caries (descriptive), primary dentition · CL/P vs no CL/P; Table 4 (7 groups/6 studies)

Retention of sealant (complete or partial retention) · Children with caries-free or non-cavitated carious lesion primary molars, aged 3-7 years (paediatric department,… · 12-24 months

Oral candidiasis prevalence · Children and adolescents (<18 years) living with HIV (CLWH) · monotherapy or dual therapy

Proportion of children with treated/untreated caries (receipt of dental care) · School children, primary schools in the USA · mean 8 months

Adverse events · Children with caries-free or non-cavitated carious lesion primary molars, aged 3-7 years (paediatric department,…

Restoration failure · Children with carious primary teeth · 5 years, Class I and II

Early childhood caries (ECC) - association at lead SNP rs9889096 (16:13575143; nearest gene(s) SHISA9) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), rs9889096 (16:13575143); effect/non-effect allele T/G; MAF 0.50; direction across 5 cohorts --+--

Progression of non-cavitated enamel caries · Children who were regular dental attenders with caries-free first or second primary molars (public health service…

Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars) · Follow-up: median 7 days

Dental attendance at orthodontist · School children, secondary school in the UK (aged 11 to 13 years) · mean 8 months