Findings

What do systematic reviews say?

1,733 questions · 1,794 findings · 326 reviews · Headline outcomes only

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No studies found 243 · 13.5%GRADE not reported 96 · 5.4%Very low 597 · 33.3%Low 506 · 28.2%Moderate 303 · 16.9%High 49 · 2.7%

Chondroitin with or without glucosamine vs placebo or control

Pain (short‐ and long‐term) Scale from 0 to 100 mm (lower is better) · patients with osteoarthritis

1 finding from 1 review

Chondroitin for osteoarthritis 2015 · Cochrane Headline outcomes only
no estimate extracted
17 studies · 2262 participants
Low

Intervention not reported

Short term treatment retention (Any psychosocial intervention vs. control)

The intervention showed no clear difference in short term treatment retention (Any psychosocial intervention vs.… (low certainty).

1 finding from 1 review

Psychosocial interventions for pregnant women in outpatient illicit drug treatment programs compared to other… 2015 · Cochrane Headline outcomes only
RR 1 [0.9, 1.1]
6 studies · 514 participants
Low

Cells vs no cells

All‐cause mortality ‐ short‐term · Anyone diagnosed with AMI

Cells showed no clear difference in all‐cause mortality ‐ short‐term compared with no cells (moderate certainty).

1 finding from 1 review

Stem cell treatment for acute myocardial infarction 2015 · Cochrane Headline outcomes only
RR 0.8 [0.43, 1.49]
17 studies · 1365 participants
Moderate

Cells vs no cells

Cardiovascular mortality · Anyone diagnosed with AMI

Cells showed no clear difference in cardiovascular mortality ‐ short‐term compared with no cells (moderate certainty).

1 finding from 1 review

Stem cell treatment for acute myocardial infarction 2015 · Cochrane Headline outcomes only
RR 0.72 [0.28, 1.82]
7 studies · 290 participants
Moderate

Cells vs no cells

Composite death, reinfarction and hospitalisation for heart failure ‐ short‐term · Anyone diagnosed with AMI

Cells showed no clear difference in composite death, reinfarction and hospitalisation for heart failure… compared with no cells (moderate certainty).

1 finding from 1 review

Stem cell treatment for acute myocardial infarction 2015 · Cochrane Headline outcomes only
RR 0.36 [0.12, 1.14]
3 studies · 379 participants
Moderate

Decompressive surgery plus radiotherapy vs radiotherapy

Survival (short term) At 30 days · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…

Decompressive surgery plus radiotherapy showed no clear difference in survival (short term) At 30 days compared with radiotherapy (low certainty).

1 finding from 1 review

Interventions for the treatment of metastatic extradural spinal cord compression in adults 2015 · Cochrane Headline outcomes only
RR 1.09 [0.96, 1.24]
1 study · 101 participants
Low

Intervention not reported

Prevalence of psychological trauma (short term: up to 3 months postpartum) Measured by various scales ‐ Impact of Event Scale (IES), MINI‐PTSD · Women of any age who had given birth within one month of the intervention being offered

The review found no eligible studies for this question.

1 finding from 1 review

Debriefing interventions for the prevention of psychological trauma in women following childbirth 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Prevalence of depression or depressive symptoms (short term: up to 3 months postpartum) Measured by various scales ‐ EPDS, HADS · Women of any age who had given birth within one month of the intervention being offered

The review found no eligible studies for this question.

1 finding from 1 review

Debriefing interventions for the prevention of psychological trauma in women following childbirth 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Prevalence of anxiety (short term: up to 3 months postpartum) Measured by HADS · Women of any age who had given birth within one month of the intervention being offered

The review found no eligible studies for this question.

1 finding from 1 review

Debriefing interventions for the prevention of psychological trauma in women following childbirth 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Prevalence of fear of childbirth (short term: up to 3 months postpartum) · Women of any age who had given birth within one month of the intervention being offered

The review found no eligible studies for this question.

1 finding from 1 review

Debriefing interventions for the prevention of psychological trauma in women following childbirth 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Prevalence of general psychological morbidity (short term: up to 3 months postpartum) · Women of any age who had given birth within one month of the intervention being offered

The review found no eligible studies for this question.

1 finding from 1 review

Debriefing interventions for the prevention of psychological trauma in women following childbirth 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Health service utilization (short term: up to 3 months postpartum) · Women of any age who had given birth within one month of the intervention being offered

The review found no eligible studies for this question.

1 finding from 1 review

Debriefing interventions for the prevention of psychological trauma in women following childbirth 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Attrition from treatment (short term: up to 3 months postpartum) · Women of any age who had given birth within one month of the intervention being offered

The review found no eligible studies for this question.

1 finding from 1 review

Debriefing interventions for the prevention of psychological trauma in women following childbirth 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Fresh frozen plasma vs no plasma

Short‐term mortality (up to 30 days) · Neonates, children and adults undergoing cardiovascular surgery

1 finding from 1 review

Fresh frozen plasma for cardiovascular surgery 2015 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 287 participants
Very low

Mortality: prone position vs supine

Short‐term mortality (STM)Alive or dead · adults with acute respiratory failure

Mortality: prone position showed no clear difference in short‐term mortality (STM)Alive or dead compared with supine (low certainty).

1 finding from 1 review

Prone position for acute respiratory failure in adults 2015 · Cochrane Headline outcomes only
RR 0.84 [0.69, 1.02]
8 studies · 2117 participants
Low

Intervention not reported

Live birth or ongoing pregnancy Short protocol vs long protocol · subfertile women

The intervention showed no clear difference in live birth or ongoing pregnancy Short protocol vs long protocol (low certainty).

1 finding from 1 review

Luteal phase support for assisted reproduction cycles 2015 · Cochrane Headline outcomes only
OR 1.04 [0.79, 1.36]
5 studies · 1205 participants
Low

Intervention not reported

Live birth/ongoing pregnancy ‐ short vs long protocol · subfertile women

The intervention showed no clear difference in live birth/ongoing pregnancy ‐ short vs long protocol (low certainty).

1 finding from 1 review

Luteal phase support for assisted reproduction cycles 2015 · Cochrane Headline outcomes only
OR 1.08 [0.81, 1.43]
1 study · 910 participants
Low

Intervention not reported

OHSS ‐ short vs long protocol · subfertile women

The review found no eligible studies for this question.

1 finding from 1 review

Luteal phase support for assisted reproduction cycles 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antihistamines vs placebo

Change in severity of overall symptoms: short‐term (1 to 2 days) Subjective severity score · patients with common cold

Antihistamines probably leads to lower change in severity of overall symptoms: short‐term Subjective… compared with placebo (moderate certainty).

1 finding from 1 review

Antihistamines for the common cold 2015 · Cochrane Headline outcomes only
OR 0.74 [0.6, 0.92]
3 studies · 1490 participants
Moderate

Sedating antihistamines vs placebo

Change in severity of overall symptoms: short‐term (1 to 2 days) Subjective severity score · patients with common cold

Sedating antihistamines leads to lower change in severity of overall symptoms: short‐term (1 to 2 days)… compared with placebo (high certainty).

1 finding from 1 review

Antihistamines for the common cold 2015 · Cochrane Headline outcomes only
OR 0.76 [0.61, 0.95]
2 studies · 1427 participants
High