Cochrane · systematic review · CD006536

Stem cell treatment for acute myocardial infarction

Fisher, SA, Zhang, H, Doree, C, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

Heart3 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 6 · 100%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

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Cells compared to no cells for acute myocardial infarction (AMI)

Population: patients with AMI
6 questions
OutcomeEffectEvidenceStatus / GRADE
All‐cause mortality ‐ short‐term
Cells vs no cells
RR 0.8 [0.43, 1.49]17 studies · 1365 participantsModerate
Downgraded: imprecision
All‐cause mortality ‐ long‐term
Cells vs no cells
RR 0.93 [0.58, 1.5]14 studies · 996 participantsModerate
Downgraded: imprecision
Cardiovascular mortality ‐ short‐term
Cells vs no cells
RR 0.72 [0.28, 1.82]7 studies · 290 participantsModerate
Downgraded: imprecision
Cardiovascular mortality ‐ long‐term
Cells vs no cells
RR 1.04 [0.54, 1.99]9 studies · 527 participantsModerate
Downgraded: imprecision
Composite death, reinfarction and hospitalisation for heart failure ‐ short‐term
Cells vs no cells
RR 0.36 [0.12, 1.14]3 studies · 379 participantsModerate
Downgraded: imprecision
Composite death, reinfarction and hospitalisation for heart failure ‐ long‐term
Cells vs no cells
RR 0.63 [0.36, 1.1]6 studies · 497 participantsModerate
Downgraded: imprecision