Search review questions

Difference in summary sensitivity (NMA, Analysis 2) · Imaging vs Transillumination

Dental caries measured by net increment in DMFS scores · Primary school children (aged 3-16 years) attending primary school in low- and middle-income countries (LMICs) · Post-intervention; follow-up varied across studies (interventions ranged from <2 years to >=2 years and longer), Intervention type: oral health education

Recurrent oral ulcerations (WHO clinical stage 2) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point)

Restoration failure · Children with carious primary teeth · 1.5 years

Caries distribution (individual/tooth/surface level) · European adolescents aged 12–19 years

Periodontal disease (gingivitis/periodontitis) · Children and adolescents (<18 years) · Cross-sectional (case-control; single time point)

Oral candidiasis prevalence · Children and adolescents (<18 years) living with HIV (CLWH) · After vs before cART (within-person), post-cART vs pre-cART

Food purchasing · Vote counting by direction of effect; unclear association of public health harm

Dental caries prevalence measured by dmft or DMFT/S score greater than one · Primary school children (aged 3-16 years) attending primary school in low- and middle-income countries (LMICs) · Post-intervention; follow-up varied across studies (interventions ranged from <2 years to >=2 years and longer)

Dental caries (association with high SES) · Children (deciduous and/or permanent dentition) in low- and middle-income countries · High SES

Caries experience · European adolescents aged 13 years · Exact age

Dental caries measured by net increment in DMFS scores · Primary school children (aged 3-16 years) attending primary school in low- and middle-income countries (LMICs) · Post-intervention; follow-up varied across studies (interventions ranged from <2 years to >=2 years and longer), WHO health-promoting-schools framework

Caries prevalence · European adolescents aged 17 years · Exact age

Clinical and radiographic success rate (>=6 months) · Human permanent teeth with irreversible pulpitis due to carious pulp exposure · >=6 months, Pulp capping material: Biodentine vs calcium hydroxide

Restoration survival · Children with caries in primary molars · 2 years, Multi-surface

Mean caries increment (mean number of new cavitated occlusal lesions) · Children with caries-free or non-cavitated carious lesion primary molars, aged 3-7 years (paediatric department,… · 24 months

Caries severity (mean DMFT) · 12-year-old children (permanent dentition) in Africa · Country: Kenya

Caries increment in permanent teeth · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of…

Treatment failure (annual failure rate) · Children with previously unrestored, vital carious lesions in primary teeth (no pulp therapy); aged 1.5-11 years · 12-36 months

Food preference · Children and adolescents aged 0-19 years · Randomized trials

Difference in summary specificity (NMA, Analysis 2) · Electrical conductance vs Imaging

Care index (CI = f/[d+m+f]) in the primary dentition · Children in the primary dentition with non-syndromic cleft lip and/or palate (CL/P) and comparable children without CL/P

Caries prevalence · European adolescents aged 12–19 years · Age group: 12–15 years

Pain during treatment · Hall Technique vs non-selective caries removal to hard dentine

Caries prevalence · European adolescents aged 12–19 years · Region: non-Scandinavian

Difference in summary sensitivity (NMA, Analysis 2) · Imaging vs Visual

Sensitivity for detecting enamel caries · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies) · Analysis 2: network meta-analysis (all studies evaluating >=2 index tests)

Contribution to total daily fluoride intake · Adults · Extreme fluoride in water (>1.5 mg/L)

Parotid hypertrophy prevalence · Children and adolescents (<18 years) living with HIV (CLWH)

Overweight/obesity risk · Healthy, term-born, normal-birth-weight infants aged 4-24 months (breastfed and/or formula-fed) in Western… · Follow-up interval 18-78 months, BLW; observational studies

Dental caries (association with good/>=2 daily brushing) · Children (deciduous and/or permanent dentition) in low- and middle-income countries

Mean annual restoration failure rate · Children (2-9 years) with caries in posterior primary teeth · First 3 years, Single-surface

Recurrent caries (crowns free of recurrent caries) · Children with primary (deciduous) teeth requiring full-coverage crown restoration · 12 months

Oral health-related quality of life · Children with dental caries · Direct estimate

Dental development and maturation · Children and adolescents (<18 years) living with HIV (CLWH)

Dental caries (association with secondary/higher maternal education) · Children (deciduous and/or permanent dentition) in low- and middle-income countries · Secondary and higher education

Mean DMFT score · Children aged 12 years (plus or minus one year) in Africa · Overall, publication-period analysis

Contribution to total daily fluoride intake · Children · Low fluoride in water (0.3-0.51 mg/L)

Infant weight-length gain (achievement of adequate weight) · Healthy, term-born, normal-birth-weight infants aged 4-24 months (breastfed and/or formula-fed) in Western… · Measured at 18-78 months of age, observational studies

Oral hygiene status · Children and adolescents (<18 years) living with HIV (CLWH)

Caries prevalence · 12-year-old children (permanent dentition) in Africa · Country: Nigeria

Oral Candida carriage and salivary yeast concentration

Caries prevalence · European adolescents aged 12–19 years · Examination type: partial-mouth

Oral health-related quality of life · Children with dental caries · Network estimate

Early childhood caries (ECC) - association at lead SNP rs8091366 (18:24715618; nearest gene(s) CHST9, KCTD1) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5… · Cross-sectional (ECC ascertained at the last dental exam before age 6), rs8091366 (18:24715618); effect/non-effect allele A/G; MAF 0.52; direction across 5 cohorts +++++

Dental caries measured by net increment in DMFS scores · Primary school children (aged 3-16 years) attending primary school in low- and middle-income countries (LMICs) · Post-intervention; follow-up varied across studies (interventions ranged from <2 years to >=2 years and longer), Non-WHO-framework interventions

Oral health-related quality of life (OHRQoL; C-ECOHIS) · Children with dental caries (ages ~2-13 years in the pooled trials) · Post-treatment

Dental caries · Children and adolescents aged 0-19 years · Nonrandomized studies

Caries prevalence · European adolescents aged 12–19 years · Examination type: full-mouth

Restoration failure · Children with carious primary teeth · 2 years, ART; Class I