Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,679 questions · 1,720 findings · 335 reviews · Headline outcomes only

No studies found 192 · 11.2%GRADE not reported 75 · 4.4%Very low 526 · 30.6%Low 504 · 29.3%Moderate 305 · 17.7%High 118 · 6.9%

ANY INTERMITTENT DRUG TECHNIQUE vs MAINTENANCE THERAPY

Leaving the study early/ loss to · patients with schizophrenia

It is very uncertain whether INTERMITTENT (DRUG HOLIDAY) changes leaving the study early/ loss to compared with MAINTENANCE THERAPY (very low certainty).

2 findings from 1 review

DANCE THERAPY vs usual care

Clinical global response‐leaving the study early (short term) · patients with schizophrenia

DANCE THERAPY showed no clear difference in clinical global response‐leaving the study early (short term) compared with STANDARD CARE (moderate certainty).

1 finding from 1 review

DANCE THERAPY vs usual care

Clinical global response‐leaving the study early (long term) · patients with schizophrenia

DANCE THERAPY showed no clear difference in clinical global response‐leaving the study early (long term) compared with STANDARD CARE (low certainty).

1 finding from 1 review

Acupuncture vs placebo or sham acupuncture

Adverse events Adverse events includes withdrawal and drop‐outs that could be clearly identified as due to an adverse event · patients with fibromyalgia

Acupuncture showed no clear difference in adverse events Adverse events includes withdrawal and drop‐outs that… compared with placebo or sham acupuncture (moderate certainty).

1 finding from 1 review

SWITCHING ANTIPSYCHOTIC: TO OLANZAPINE vs MAINTENANCE RISPERIDONE/FGA

Leaving the study early · patients with sexual dysfunction due to antipsychotic drug therapy

It is very uncertain whether SWITCHING ANTIPSYCHOTIC: TO OLANZAPINE changes leaving the study early compared with MAINTENANCE RISPERIDONE/FGA (very low certainty).

1 finding from 1 review