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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
75,239 questions in 5,342 reviews
current versionsNo studies 15,213 · 20.2%Ungraded 10,323 · 13.7%Very low 17,528 · 23.3%Low 17,951 · 23.9%Moderate 11,190 · 14.9%High 3,034 · 4%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Multidisciplinary interventions vs care RTW · people with cancer Non‐medical interventions to enhance return to work for people with cancer (2024) · Cochrane | RR 1.23 [1.09, 1.33] | 6 studies · 497 participants | Moderate |
Multidisciplinary interventions vs care QoL · people with cancer Non‐medical interventions to enhance return to work for people with cancer (2024) · Cochrane | no estimate extracted | 3 studies · 378 participants | Low |
Summary of findings table ‐ Therapeutic exercise vs no treatment Cobb angle · adolescents with idiopathic scoliosis Therapeutic exercises for idiopathic scoliosis in adolescents (2024) · Cochrane | no estimate extracted | 2 studies · 52 participants | Very low |
Summary of findings table ‐ Therapeutic exercise plus non‐surgical intervention vs non‐surgical intervention Angle of trunk rotation – PSSE plus other non‐surgical vs other non‐surgical · adolescents with idiopathic scoliosis Therapeutic exercises for idiopathic scoliosis in adolescents (2024) · Cochrane | no estimate extracted | 1 study · 18 participants | Very low |
Summary of findings table ‐ Therapeutic exercise plus non‐surgical intervention vs non‐surgical intervention Subjective evaluation (SAQ General) – PSSE plus bracing vs bracing alone · adolescents with idiopathic scoliosis Therapeutic exercises for idiopathic scoliosis in adolescents (2024) · Cochrane | no estimate extracted | 1 study · 34 participants | Low |
Summary of findings table ‐ Therapeutic exercise plus non‐surgical intervention vs non‐surgical intervention Subjective evaluation (SRS‐22 Self‐Image) – PSSE plus bracing vs bracing · adolescents with idiopathic scoliosis Therapeutic exercises for idiopathic scoliosis in adolescents (2024) · Cochrane | no estimate extracted | 1 study · 34 participants | Low |
Summary of findings table ‐ Therapeutic exercise plus non‐surgical intervention vs non‐surgical intervention Quality of life (SRS‐22 Total score) – PSSE plus bracing vs bracing · adolescents with idiopathic scoliosis Therapeutic exercises for idiopathic scoliosis in adolescents (2024) · Cochrane | no estimate extracted | 1 study · 34 participants | Low |
Summary of findings table ‐ Therapeutic exercise vs bracing Cobb angle – PSSE vs bracing · adolescents with idiopathic scoliosis Therapeutic exercises for idiopathic scoliosis in adolescents (2024) · Cochrane | no estimate extracted | 1 study · 60 participants | Very low |
Summary of findings table ‐ Therapeutic exercise vs bracing Subjective surface measurements (SRS‐22 Self‐Image) – PSSE vs bracing · adolescents with idiopathic scoliosis Therapeutic exercises for idiopathic scoliosis in adolescents (2024) · Cochrane | no estimate extracted | 1 study · 60 participants | Very low |
Summary of findings table ‐ Therapeutic exercise vs bracing Quality of life (SRS‐22 Total score) – PSSE vs bracing · adolescents with idiopathic scoliosis Therapeutic exercises for idiopathic scoliosis in adolescents (2024) · Cochrane | no estimate extracted | 1 study · 60 participants | Very low |
Summary of findings table ‐ Physiotherapeutic scoliosis‐specific exercises (PSSE) vs general therapeutic exercises (GTE) Cobb angle · adolescents with idiopathic scoliosis Therapeutic exercises for idiopathic scoliosis in adolescents (2024) · Cochrane | no estimate extracted | 4 studies · 192 participants | Very low |
Summary of findings table ‐ Physiotherapeutic scoliosis‐specific exercises (PSSE) vs general therapeutic exercises (GTE) Angle of trunk rotation · adolescents with idiopathic scoliosis Therapeutic exercises for idiopathic scoliosis in adolescents (2024) · Cochrane | no estimate extracted | 2 studies · 138 participants | Moderate |
Summary of findings table ‐ Physiotherapeutic scoliosis‐specific exercises (PSSE) vs general therapeutic exercises (GTE) Number progressed > 5° Cobb angle · adolescents with idiopathic scoliosis Therapeutic exercises for idiopathic scoliosis in adolescents (2024) · Cochrane | RR 0.19 [0.07, 0.52] | 1 study · 110 participants | Low |
Summary of findings table ‐ Therapeutic exercise vs no treatment Angle of trunk rotation · adolescents with idiopathic scoliosis Therapeutic exercises for idiopathic scoliosis in adolescents (2024) · Cochrane | no estimate extracted | 1 study · 45 participants | Low |
Summary of findings table ‐ Physiotherapeutic scoliosis‐specific exercises (PSSE) vs general therapeutic exercises (GTE) Subjective surface measurement · adolescents with idiopathic scoliosis Therapeutic exercises for idiopathic scoliosis in adolescents (2024) · Cochrane | no estimate extracted | 3 studies · 168 participants | Very low |
Summary of findings table ‐ Physiotherapeutic scoliosis‐specific exercises (PSSE) vs general therapeutic exercises (GTE) Quality of life (SRS‐22 Total score) · adolescents with idiopathic scoliosis Therapeutic exercises for idiopathic scoliosis in adolescents (2024) · Cochrane | no estimate extracted | 3 studies · 168 participants | Very low |
Summary of findings table ‐ Therapeutic exercise vs no treatment Objective surface measurements (waist asymmetry) · adolescents with idiopathic scoliosis Therapeutic exercises for idiopathic scoliosis in adolescents (2024) · Cochrane | no estimate extracted | 1 study · 45 participants | Low |
Summary of findings table ‐ Therapeutic exercise vs no treatment Subjective evaluation (SAQ General) · adolescents with idiopathic scoliosis Therapeutic exercises for idiopathic scoliosis in adolescents (2024) · Cochrane | no estimate extracted | 1 study · 16 participants | Low |
Summary of findings table ‐ Therapeutic exercise vs no treatment Subjective evaluation (SRS‐22 Self‐Image) · adolescents with idiopathic scoliosis Therapeutic exercises for idiopathic scoliosis in adolescents (2024) · Cochrane | no estimate extracted | 1 study · 16 participants | Low |
Summary of findings table ‐ Therapeutic exercise vs no treatment Quality of life (SRS‐22 Total score) · adolescents with idiopathic scoliosis Therapeutic exercises for idiopathic scoliosis in adolescents (2024) · Cochrane | no estimate extracted | 2 studies · 61 participants | Low |
Summary of findings table ‐ Therapeutic exercise plus non‐surgical intervention vs non‐surgical intervention Cobb angle ‐ PSSE plus bracing vs bracing · adolescents with idiopathic scoliosis Therapeutic exercises for idiopathic scoliosis in adolescents (2024) · Cochrane | no estimate extracted | 2 studies · 84 participants | Low |
Summary of findings table ‐ Therapeutic exercise plus non‐surgical intervention vs non‐surgical intervention Cobb angle – PSSE plus other non‐surgical vs non‐surgical · adolescents with idiopathic scoliosis Therapeutic exercises for idiopathic scoliosis in adolescents (2024) · Cochrane | no estimate extracted | 1 study · 18 participants | Very low |
Summary of findings table ‐ Therapeutic exercise plus non‐surgical intervention vs non‐surgical intervention Cobb angle ‐ GTE plus other non‐surgical vs non‐surgical · adolescents with idiopathic scoliosis Therapeutic exercises for idiopathic scoliosis in adolescents (2024) · Cochrane | no estimate extracted | 1 study · 80 participants | Low |
Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with the intent to rapidly extubate (InSurE) Death or bronchopulmonary dysplasia · preterm infants with or at risk of respiratory distress syndrome Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants… (2024) · Cochrane | RR 1.5 [0.27, 8.34] | 2 studies · 110 participants | Low |
Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with extubation at standard criteria (S‐ETT) Pulmonary air leak, any (during first hospitalisation) Anytime to discharge · preterm infants with or at risk of respiratory distress syndrome Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants… (2024) · Cochrane | RR 2.56 [0.11, 59.75] | 1 study · 48 participants | Very low |
Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with extubation at standard criteria (S‐ETT) Bronchopulmonary dysplasia (clinical definition) among survivors · preterm infants with or at risk of respiratory distress syndrome Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants… (2024) · Cochrane | no estimate extracted | NR | No studies |
Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with extubation at standard criteria (S‐ETT) Intraventricular haemorrhage grade III and IV Anytime to discharge · preterm infants with or at risk of respiratory distress syndrome Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants… (2024) · Cochrane | RR 2.56 [0.11, 59.75] | 1 study · 48 participants | Very low |
Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with extubation at standard criteria (S‐ETT) Death (all causes) during the first hospitalisation Anytime to discharge · preterm infants with or at risk of respiratory distress syndrome Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants… (2024) · Cochrane | RR 0.17 [0.01, 3.37] | 1 study · 48 participants | Very low |
Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with extubation at standard criteria (S‐ETT) Neurosensory disability in survivors · preterm infants with or at risk of respiratory distress syndrome Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants… (2024) · Cochrane | no estimate extracted | NR | No studies |
Surfactant administration via laryngeal mask airway (S‐LMA) vs no surfactant administration Death or bronchopulmonary dysplasia · preterm infants with or at risk of respiratory distress syndrome Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants… (2024) · Cochrane | RR 1.65 [0.85, 3.22] | 2 studies · 129 participants | Low |
Surfactant administration via laryngeal mask airway (S‐LMA) vs no surfactant administration Mechanical ventilation at any time At any time to discharge · preterm infants with or at risk of respiratory distress syndrome Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants… (2024) · Cochrane | RR 0.57 [0.38, 0.85] | 2 studies · 129 participants | Moderate |
Surfactant administration via laryngeal mask airway (S‐LMA) vs no surfactant administration Pulmonary air leak, any (during first hospitalisation) Anytime to discharge · preterm infants with or at risk of respiratory distress syndrome Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants… (2024) · Cochrane | RR 0.65 [0.23, 1.88] | 2 studies · 129 participants | Low |
Surfactant administration via laryngeal mask airway (S‐LMA) vs no surfactant administration Bronchopulmonary dysplasia (clinical definition) among survivors · preterm infants with or at risk of respiratory distress syndrome Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants… (2024) · Cochrane | RR 1.65 [0.85, 3.22] | 2 studies · 129 participants | Low |
Surfactant administration via laryngeal mask airway (S‐LMA) vs no surfactant administration Intraventricular haemorrhage grade III and IV Anytime to discharge · preterm infants with or at risk of respiratory distress syndrome Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants… (2024) · Cochrane | no estimate extracted | 1 study · 103 participants | Very low |
Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with the intent to rapidly extubate (InSurE) Mechanical ventilation at any time Any time to discharge · preterm infants with or at risk of respiratory distress syndrome Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants… (2024) · Cochrane | RR 0.53 [0.36, 0.78] | 5 studies · 333 participants | Low |
Surfactant administration via laryngeal mask airway (S‐LMA) vs no surfactant administration Death (all causes) during the first hospitalisation Anytime to discharge · preterm infants with or at risk of respiratory distress syndrome Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants… (2024) · Cochrane | no estimate extracted | 1 study · 103 participants | Very low |
Surfactant administration via laryngeal mask airway (S‐LMA) vs no surfactant administration Neurosensory disability in survivors · preterm infants with or at risk of respiratory distress syndrome Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants… (2024) · Cochrane | no estimate extracted | NR | No studies |
Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with the intent to rapidly extubate (InSurE) Pulmonary air leak, any (during first hospitalisation) Anytime to discharge · preterm infants with or at risk of respiratory distress syndrome Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants… (2024) · Cochrane | RR 1.39 [0.65, 2.98] | 5 studies · 333 participants | Low |
Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with the intent to rapidly extubate (InSurE) Bronchopulmonary dysplasia (clinical definition) among survivors · preterm infants with or at risk of respiratory distress syndrome Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants… (2024) · Cochrane | RR 1.28 [0.47, 3.52] | 4 studies · 264 participants | Low |
Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with the intent to rapidly extubate (InSurE) Intraventricular haemorrhage grade III and IV Anytime to discharge · preterm infants with or at risk of respiratory distress syndrome Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants… (2024) · Cochrane | no estimate extracted | 1 study · 50 participants | Very low |
Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with the intent to rapidly extubate (InSurE) Death (all causes) during the first hospitalisation Anytime to discharge · preterm infants with or at risk of respiratory distress syndrome Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants… (2024) · Cochrane | RR 0.28 [0.01, 6.6] | 3 studies · 203 participants | Low |
Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with the intent to rapidly extubate (InSurE) Neurosensory disability in survivors · preterm infants with or at risk of respiratory distress syndrome Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants… (2024) · Cochrane | no estimate extracted | NR | No studies |
Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with extubation at standard criteria (S‐ETT) Death or bronchopulmonary dysplasia · preterm infants with or at risk of respiratory distress syndrome Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants… (2024) · Cochrane | no estimate extracted | NR | No studies |
Surfactant administration via laryngeal mask airway (S‐LMA) vs surfactant administration via endotracheal tube (ETT) with extubation at standard criteria (S‐ETT) Mechanical ventilation at any time Any time to discharge · preterm infants with or at risk of respiratory distress syndrome Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants… (2024) · Cochrane | RR 0.47 [0.31, 0.71] | 1 study · 48 participants | Low |
Summary of findings table ‐ GABA‐analogues vs placebo Pruritus · health problem or population Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane | no estimate extracted | 5 studies · 297 participants | Moderate |
Summary of findings table ‐ Gabapentin vs pregabalin Risk for at least one adverse event per patient · patients with chronic kidney disease (CKD) pruritus Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane | RR 4.7 [0.21, 104.14] | 2 studies · 122 participants | Very low |
Summary of findings table ‐ Kappa‐opioid agonists vs placebo Pruritus · patients with chronic kidney disease (CKD) pruritus Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane | no estimate extracted | 6 studies · 1292 participants | High |
Summary of findings table ‐ Kappa‐opioid agonists vs placebo Quality of life ‐ not measured · patients with chronic kidney disease (CKD) pruritus Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Kappa‐opioid agonists vs placebo Patient satisfaction ‐ not measured · patients with chronic kidney disease (CKD) pruritus Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings table ‐ Kappa‐opioid agonists vs placebo Depression ‐ not measured · patients with chronic kidney disease (CKD) pruritus Pharmacological interventions for pruritus in adult palliative care patients (2024) · Cochrane | no estimate extracted | NR | No studies |