Improvement in sensory nerve function at 1 year · people with nerve damage (< 6 months' duration) in leprosy
Corticosteroids showed no clear difference in improvement in sensory nerve function at 1 year Defined as a… compared with placebo (moderate certainty).
1 finding from 1 review
Adverse events Assessed as: occurrence of one or more major adverse events requiring withdrawal of treatment · people with nerve damage (< 6 months' duration) in leprosy
Corticosteroids showed no clear difference in adverse events Assessed as: occurrence of one or more major adverse… compared with placebo (moderate certainty).
1 finding from 1 review
Number of participants with 3 or more adenomas (in studies with single intubation) · people undergoing colonoscopy for the detection of polyps
Chromoscopy may leads to higher number of participants with 3 or more adenomas (in studies with… compared with conventional colonoscopy (low certainty).
1 finding from 1 review
“Food allergy” to 1 or more foods between 1 to 3 years of age · healthy breastfeeding full‐term infants
Non‐exclusive breastfeeding (foods) showed no clear difference in “Food allergy” to 1 or more foods between 1 to 3 years of age compared with exclusive breastfeeding (moderate certainty).
1 finding from 1 review
Major bleeding fall in hemoglobin of > 20 g/L or transfusion of 2 or more units of red cells · patients with venous thromboembolism.
10 mg warfarin nomogram showed no clear difference in major bleeding fall in hemoglobin of > 20 g/L or transfusion of 2 or… compared with 5 mg warfarin nomogram (moderate certainty).
1 finding from 1 review
Complete resolution of OME at more than 6 months · Children with otitis media with effusion
Antibiotics may leads to higher complete resolution of OME at more than 6 months compared with placebo, no treatment or therapy of unproven effectiveness (low certainty).
1 finding from 1 review
Intervention not reported
Loss of 1 or more lines of BSCVA at 12 months post treatment · adult participants (≥ 18 years) with myopia
It is very uncertain whether the intervention changes loss of 1 or more lines of BSCVA at 12 months post treatment (very low certainty).
1 finding from 1 review
RR 3 [0.13, 71.96]
Studies not reported
Very low
Intervention not reported
Adverse outcomes ‐ corneal haze score at 12 months (grade 1.0 ‐ more prominent haze that does not interfere with visibility of fine iris details; grade 2.0 ‐ mild obscuration of iris details; grade 3.0 ‐ moderate obscuration of iris and lens; and ... · adult participants (≥ 18 years) with myopia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Intervention not reported
dmft measured at more than 1 year of · children
1 finding from 1 review
no estimate extracted
99481 participants
Low
Intervention not reported
Contraceptive use: more effective method · women with need for family planning (FP)
The intervention probably leads to higher contraceptive use: more effective method (moderate certainty).
1 finding from 1 review
OR 1.81 [1.24, 2.63]
18 participants
Moderate
Intervention not reported
Communication Validated self‐report measure: verbal subscale of the CPHI scale from 0 to 5 (Demorest 1987) · adults with hearing loss who use hearing aids
1 finding from 1 review
Intervention not reported
Use of verbal communication strategy Validated self‐report measures (verbal subscale of the CPHI (Demorest 1987)). Scale from: 0 to 5 · adults with hearing loss who use hearing aids
1 finding from 1 review
Intervention not reported
Communication Validated self‐report measure: verbal subscale of the CPHI (Demorest 1987) scale from 0 to 5 · adults with hearing loss who use hearing aids
1 finding from 1 review
Activity: long term (5 or more years · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee
It is very uncertain whether mosaicplasty changes activity: long term (5 or more years compared with microfracture (very low certainty).
1 finding from 1 review
50% reduction in seizures frequency (12 weeks) ‐ Per protocol data ‐ Older (19 years or more) · patients with drug‐resistant epilepsy
PUFA showed no clear difference in 50% reduction in seizures frequency (12 weeks) ‐ Per protocol data ‐… compared with placebo (low certainty).
1 finding from 1 review
Intervention not reported
Serious Adverse Events (Participants with one or more event) · Adults (>18 years) with pulmonary hypertension of varied aetiology (PAH, CTEPH and left heart disease)
It is very uncertain whether the intervention changes serious Adverse Events (Participants with one or more event) (very low certainty).
1 finding from 1 review
Intervention not reported
Sleep problems (Scale 0 to 21; higher scores indicate more sleep problems) · adults with fibromyalgia
1 finding from 1 review
Proportion of participants with 1 or more adverse events at 2‐12 weeks · people with venous leg ulcers
Protease‐modulating matrix dressing regimen showed no clear difference in proportion of participants with 1 or more adverse events at 2‐12 weeks compared with any other dressing regimen (low certainty).
1 finding from 1 review
Improvement More than 1 category change in pain intensity on 4‐point scale (no pain/sporadic/daily/continuous) · patients with rheumatoid arthritis
Additional radon in carbon dioxide baths showed no clear difference in improvement More than 1 category change in pain intensity on 4‐point… compared with carbon dioxide baths only (low certainty).
2 findings from 1 review
Pain intensity various scales short‐term · patients with LBP
1 finding from 1 review