Cochrane · systematic review · CD011804
Antipsychotics for fibromyalgia in adults
Walitt, B, Klose, P, Üçeyler, N, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
Pain, Palliative and Supportive CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 6 · 85.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: adults with fibromyalgia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
At least 50 % pain relief | no estimate extracted | 2 studies · 155 participants | Very low Downgraded: risk of bias |
Patient Global Impression of Change much or very much improved | no estimate extracted | NR | No studies |
Sleep problems (Scale 0 to 21; higher scores indicate more sleep problems) | no estimate extracted | 2 studies · 87 participants | Very low Downgraded: risk of bias |
Depression (Scale 0 to 50) | no estimate extracted | 3 studies · 207 participants | Very low Downgraded: risk of bias |
Withdrawals due to adverse events | no estimate extracted | 2 studies · 155 participants | Very low Downgraded: risk of bias |
Serious adverse events | no estimate extracted | 3 studies · 206 participants | Very low Downgraded: risk of bias |
Substantial weight gain | no estimate extracted | 2 studies · 155 participants | Very low Downgraded: risk of bias |