Cochrane · systematic review · CD006439

Chromoscopy versus conventional endoscopy for the detection of polyps in the colon and rectum

Brown, SR, Baraza, W, Din, S, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

ColorectalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
7
No studies
1
Included studies
NR
No studies 1 · 12.5%Ungraded 0 · 0%Very low 0 · 0%Low 7 · 87.5%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Chromoscopy compared to conventional colonoscopy for the detection of polyps

Population: people undergoing colonoscopy for the detection of polyps
8 questions
OutcomeEffectEvidenceStatus / GRADE
Total polyps (neoplastic and non‐neoplastic) detected
Chromoscopy vs conventional colonoscopy
MD 0.89 [0.74, 1.04]7 studies · 2727 participantsLow
Downgraded: imprecision, inconsistency
Total neoplastic lesions
Chromoscopy vs conventional colonoscopy
MD 0.33 [0.25, 0.41]7 studies · 2727 participantsLow
Downgraded: imprecision, inconsistency
Number of participants with at least 1 polyp (neoplastic or non‐neoplastic)
Chromoscopy vs conventional colonoscopy
OR 1.87 [1.51, 2.3]4 studies · 1515 participantsLow
Downgraded: imprecision, inconsistency
Total participants with at least 1 neoplastic lesion
Chromoscopy vs conventional colonoscopy
OR 1.53 [1.31, 1.79]7 studies · 2727 participantsLow
Downgraded: imprecision, inconsistency
Number of diminutive neoplastic lesions
Chromoscopy vs conventional colonoscopy
MD 0.21 [0.1, 0.32]4 studies · 1409 participantsLow
Downgraded: imprecision, inconsistency
Participants with diminutive neoplastic lesions
Chromoscopy vs conventional colonoscopy
OR 1.51 [1.19, 1.92]4 studies · 1757 participantsLow
Downgraded: imprecision, inconsistency
Number of participants with 3 or more adenomas (in studies with single intubation)
Chromoscopy vs conventional colonoscopy
OR 4.63 [1.99, 10.8]2 studies · 519 participantsLow
Downgraded: imprecision, inconsistency
Adverse events
Chromoscopy vs conventional colonoscopy
no estimate extractedNRNo studies