Number of participants with exacerbations requiring systemic steroids · patients with chronic asthma
LABA + ICS leads to lower participants with one or more exacerbations requiring systemic… compared with LTRA + ICS (high certainty).
1 finding from 1 review
Exacerbations (number of people experiencing ≥ 1 exacerbations) · people with COPD who have smoked for ≥ 10 pack‐years
Tiotropium leads to lower number of patients with one or more exacerbations compared with placebo (high certainty).
1 finding from 1 review
Hospital admissions due to exacerbations: number of participants · people with COPD who have smoked for ≥ 10 pack‐years
Tiotropium showed no clear difference in number of patients with one or more exacerbations requiring… compared with placebo (moderate certainty).
1 finding from 1 review
Hospital admissions · people with COPD who have smoked for ≥ 10 pack‐years
Tiotropium showed no clear difference in number of patients with one or more hospitalisations for any cause compared with placebo (moderate certainty).
1 finding from 1 review
Intervention not reported
SGRQ Scores range from 0 to 100, with higher scores indicating more limitations · 18 to 80 years of age with bronchiectasis
The intervention showed no clear difference in SGRQ Scores range from 0 to 100, with higher scores indicating more… (low certainty).
1 finding from 1 review
Intervention not reported
Hospitalisations, number of participants with 1 or more exacerbations · 18 to 80 years of age with bronchiectasis
The intervention showed no clear difference in hospitalisations, number of participants with 1 or more exacerbations (low certainty).
1 finding from 1 review
Hospital admissions · the management of asthma
1 finding from 1 review
Number of participants experiencing one or more episode requiring treatment with oral steroids · children with asthma
Anti‐leukotrienes & ICS may leads to lower participants with one or more exacerbations requiring oral… compared with same dose ICS (low certainty).
1 finding from 1 review
Number of participants experiencing one or more episode requiring treatment with oral steroids · children with asthma
Anti‐leukotrienes & ICS may leads to lower participants with one or more exacerbations requiring oral… compared with higher dose ICS (low certainty).
1 finding from 1 review
Number of participants experiencing one or more episode requiring treatment with oral steroids · Children and adults with persistent asthma.
Intermittent 'as needed' ICS showed no clear difference in patients with 1 or more exacerbations requiring oral corticosteroids… compared with daily ICS (low certainty).
1 finding from 1 review
Participants with one or more serious adverse event (non‐fatal) · patients with chronic obstructive pulmonary disease
Long‐acting beta2‐agonists showed no clear difference in participants with one or more serious adverse event (non‐fatal) compared with placebo (moderate certainty).
1 finding from 1 review
Number of participants experiencing one or more episodes requiring ED visit · people with asthma
It is very uncertain whether asthma Clinics (Intervention) changes A&E visits Number of people experiencing one or more A&E visit compared with controls (very low certainty).
1 finding from 1 review
Hospital admissions · people with asthma
Asthma Clinics (Intervention) showed no clear difference in hospital admissions Number of people experiencing one or more… compared with controls (low certainty).
1 finding from 1 review
Days lost from work Number of people reporting one or more instances of time off work or school · people with asthma
1 finding from 1 review
Intervention not reported
Readmission to hospital, inpatient. Number of people experiencing one or more readmissions ( · exacerbations of COPD
The intervention probably leads to lower readmission to hospital, inpatient. Number of people experiencing… (moderate certainty).
1 finding from 1 review
Exacerbations (number of people experiencing ≥ 1 exacerbations) · COPD
Combined inhalers probably leads to lower number of people experiencing one or more exacerbations compared with LABAs (moderate certainty).
1 finding from 1 review
Hospitalisations, number of participants with 1 or more exacerbations · patients with stable chronic obstructive pulmonary disease and > 10 pack years smoking history
Tiotropium probably leads to lower patients with 1 or more exacerbations compared with long‐acting beta‐agonists (moderate certainty).
1 finding from 1 review
Intervention not reported
Number of subjects who had one or more exacerbations over the study period in adults ( · Adults and children with asthma
The intervention showed no clear difference in number of subjects who had one or more exacerbations over the study… (moderate certainty).
1 finding from 1 review
Intervention not reported
Number of subjects who had one or more exacerbations over the study period in children and adolescents ( · Adults and children with asthma
The intervention showed no clear difference in number of subjects who had one or more exacerbations over the study… (moderate certainty).
1 finding from 1 review
Annual Exacerbation Rates · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…
Antibiotics probably leads to lower rate of exacerbation per patient/year WMD of compared with placebo (moderate certainty).
1 finding from 1 review