Cochrane · systematic review · CD006340
Tailored interventions based on exhaled nitric oxide versus clinical symptoms for asthma in children and adults
Petsky, HL, Cates, CJ, Li, A, et al. · Cochrane Database of Systematic Reviews · 2009 · Cochrane Library
AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 16.7%Moderate 5 · 83.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: Adults and children with asthma
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Number of subjects who had one or more exacerbations over the study period in adults ( | OR 0.85 [0.3, 2.43] | 2 studies · 197 participants | Moderate |
Number of subjects who had one or more exacerbations over the study period in children and adolescents ( | OR 0.75 [0.55, 1.01] | 3 studies · 782 participants | Moderate Downgraded: risk of bias, imprecision |
Number of exacerbations per 52 weeks in adults ( | no estimate extracted | 2 studies · 197 participants | Moderate |
Number of exacerbations per 52 weeks in children and adolescents ( | no estimate extracted | 1 study · 546 participants | Moderate Downgraded: risk of bias, imprecision |
ICS dose at final visit in adults ( | no estimate extracted | 2 studies · 197 participants | Moderate Downgraded: risk of bias, imprecision |
ICS dose at final visit in children and adolescents ( | no estimate extracted | 3 studies · 777 participants | Low Downgraded: risk of bias, imprecision |