Cochrane · systematic review · CD010327

Combination inhaled corticosteroids and long‐acting beta₂‐agonists for children and adults with bronchiectasis

Goyal, V, Chang, AB · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 4 · 100%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Comparison

Population: 18 to 80 years of age with bronchiectasis
4 questions
OutcomeEffectEvidenceStatus / GRADE
SGRQ Scores range from 0 to 100, with higher scores indicating more limitations
no estimate extracted1 study · 40 participantsLow
Downgraded: imprecision
TDI Total scores range from ‐ 9 to +9. The lower the score, the greater the deterioration in severity of dyspnoea, MCID ≥ 1
MD 1.29 [0.4, 2.18]1 study · 40 participantsLow
Downgraded: imprecision
Cough‐free days Percentage of days free of cough
MD 12.3 [2.38, 22.22]1 study · 40 participantsLow
Downgraded: imprecision
Hospitalisations, number of participants with 1 or more exacerbations
OR 0.26 [0.02, 2.79]1 study · 38 participantsLow
Downgraded: imprecision