evidencegaps
Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

2,509 questions · 2,666 findings · 288 reviews

Sort:Best matchNewestHighest certaintyDownload CSV
No studies found 743 · 27.9%GRADE not reported 327 · 12.3%Very low 775 · 29.1%Low 484 · 18.2%Moderate 279 · 10.5%High 58 · 2.2%

Endodontic therapy (surgical or non-surgical) performed with the aid of one or more magnification devices (surgical microscope, endoscope or magnifying loupes) vs The same endodontic therapy performed without magnification devices (without visual enhancers)

Overall success (composite of clinical and radiographic success) · Patients of any age who received endodontic therapy and were followed up for at least 1 year after treatment

The review found no eligible studies for this question.

1 finding from 1 review
  • Magnification devices for endodontic therapy 2015 · Cochrane All outcomes
    >=1 year after treatment
    None of the studies fulfilled our inclusion criteria and therefore no data analysis was conducted (three potentially eligible trials were identified from 1234 records; all were excluded).
    Studies not reported
    No studies found

Summary of findings table ‐ Purse‐string skin closure vs linear skin closure

Surgical site infection · people undergoing stoma reversal

Summary of findings table ‐ Purse‐string skin closure probably leads to lower surgical site infection compared with linear skin closure (moderate certainty).

1 finding from 1 review

Tranexamic acid vs placebo (saline solution or sterile water)

Overall rate of surgical complications · adults and children with chronic rhinosinusitis with or without nasal polyps

Tranexamic acid showed no clear difference in surgical complications compared with placebo (saline solution or sterile water) (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Combined mechanical and oral antibiotic bowel preparation vs no bowel preparation

Surgical site infection · Patients undergoing elective colorectal surgery

Summary of findings table ‐ Combined mechanical and oral antibiotic… showed no clear difference in surgical site infections compared with no bowel preparation (low certainty).

1 finding from 1 review

Summary of findings table ‐ Combined mechanical and oral antibiotic bowel preparation vs oral antibiotics

Surgical site infection · Patients undergoing elective colorectal surgery

It is very uncertain whether summary of findings table ‐ Combined mechanical and oral antibiotic… changes surgical site infections compared with oral antibiotics alone (very low certainty).

1 finding from 1 review

Antifibrinolytic therapy - locally-applied tranexamic acid (TXA) mouthwash/solution (SoF eligibility: TXA or EACA; all included trials used topical TXA) vs placebo or usual care

Major surgical complications · Percutaneous nephrolithotomy

Topical TXA showed no clear difference in major surgical complications compared with no TXA (placebo or usual care) (low certainty).

1 finding from 1 review

Antifibrinolytic therapy - locally-applied tranexamic acid (TXA) mouthwash/solution (SoF eligibility: TXA or EACA; all included trials used topical TXA) vs placebo or usual care

Minor surgical complications · Percutaneous nephrolithotomy

Topical TXA may leads to lower minor surgical complications compared with no TXA (placebo or usual care) (low certainty).

1 finding from 1 review

Summary of findings table ‐ mesh repair vs non‐mesh repair

Surgical site infection · adult patients with incarcerated or strangulated groin hernia

It is very uncertain whether summary of findings table ‐ mesh repair changes surgical site infections within 30 days of repair compared with non‐mesh repair (very low certainty).

1 finding from 1 review

Nitrous oxide vs carbon dioxide

Procedure‐related general complications · people undergoing laparoscopic general abdominal or gynaecological pelvic surgery under general anaesthesia

It is very uncertain whether nitrous oxide changes procedure‐related general complications (surgical morbidity) compared with carbon dioxide (very low certainty).

1 finding from 1 review

Subgroup analyses: early vs standard initiation of kidney replacement therapy (KRT)

Death by AKI aetiology: non‐surgical causes · AKI

Subgroup analyses: early showed no clear difference in death by AKI aetiology: non‐surgical causes compared with standard initiation of kidney replacement therapy (KRT) (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Remifentanil vs diazepam

Surgical assessment/satisfaction score = 1 or 2 (Technically successful procedure as defined by trial authors) · health problem or population

Summary of findings table ‐ Remifentanil may leads to higher surgical assessment/satisfaction score = 1 or 2 (Technically… compared with diazepam (low certainty).

1 finding from 1 review