Cochrane · systematic review · CD011068
Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures
Andrewartha, K, Grivell, RM · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
5
No studies
2
Included studies
NR
No studies 2 · 28.6%Ungraded 0 · 0%Very low 0 · 0%Low 5 · 71.4%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings table ‐ Remifentanil compared to diazepam for fetal immobilisation during fetal surgery and invasive procedures
Population: health problem or population
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Fetal immobilisation score at 40 minutes (Degree of fetal immobilisation as defined by trial authors) Summary of findings table ‐ Remifentanil vs diazepam | no estimate extracted | 1 study · 50 participants | Low Downgraded: imprecision |
Fetal movements ‐ gross body and limb (Degree of fetal immobilisation as defined by trial authors) Summary of findings table ‐ Remifentanil vs diazepam | no estimate extracted | 1 study · 50 participants | Low Downgraded: imprecision |
Surgical assessment/satisfaction score = 1 or 2 (Technically successful procedure as defined by trial authors) Summary of findings table ‐ Remifentanil vs diazepam | RR 2.88 [1.6, 5.15] | 1 study · 50 participants | Low Downgraded: imprecision |
Maternal respiratory rate (Maternal respiratory depression as defined by trial authors or measured using intraoperative maternal arterial oxygen saturation and maternal respiratory rate) Summary of findings table ‐ Remifentanil vs diazepam | no estimate extracted | 1 study · 50 participants | Low Downgraded: imprecision |
Maternal OAA score (observer assessment of alertness/sedation) < 4 (Maternal sedation measured using sedation scores as defined by authors) Summary of findings table ‐ Remifentanil vs diazepam | RR 0.09 [0.01, 0.65] | 1 study · 50 participants | Low Downgraded: imprecision |
Perinatal mortality Summary of findings table ‐ Remifentanil vs diazepam | no estimate extracted | NR | No studies |
Time taken to perform procedure Summary of findings table ‐ Remifentanil vs diazepam | no estimate extracted | NR | No studies |