Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,511 questions · 2,668 findings · 290 reviews

No studies found 743 · 27.8%GRADE not reported 329 · 12.3%Very low 775 · 29%Low 484 · 18.1%Moderate 279 · 10.5%High 58 · 2.2%

Non‐surgical vs surgical treatment of oesophageal cancer (primary outcomes)

Long‐term recurrence (> 5 years) · patients with oesophageal cancer

It is very uncertain whether non‐surgical changes long‐term recurrence (binary outcome) Local recurrence, surgical… compared with surgical treatment of oesophageal cancer (secondary outcomes) (very low certainty).

1 finding from 1 review

Non‐surgical vs surgical treatment of oesophageal cancer (primary outcomes)

Long‐term recurrence (maximal · patients with oesophageal cancer

Non‐surgical showed no clear difference in long‐term recurrence (time‐to‐event outcome) Local recurrence,… compared with surgical treatment of oesophageal cancer (secondary outcomes) (low certainty).

1 finding from 1 review

Open surgical exposure vs Closed surgical exposure

Treatment time: time from surgical exposure to eruption/bonding a bracket · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

Open surgical exposure led to lower treatment time: time from surgical exposure to eruption/bonding a… compared with closed surgical exposure; GRADE not reported.

1 finding from 1 review

Surgical vs non‐surgical treatment

Number of participants sustaining recurrent patellar dislocation · people with lateral patellar dislocation

It is very uncertain whether surgical changes number of participants sustaining recurrent patellar dislocationa compared with non‐surgical treatment (very low certainty).

1 finding from 1 review

Surgical vs non‐surgical treatment

Kujala patellofemoral disorders score Scale from: 0 to 100 (higher scores = better function) · people with lateral patellar dislocation

It is very uncertain whether surgical changes knee and physical functiona Measured using the Kujala patellofemoral… compared with non‐surgical treatment (very low certainty).

1 finding from 1 review

Surgical vs non‐surgical treatment

Adverse effects of treatment Overall incidence of complications · people with lateral patellar dislocation

It is very uncertain whether surgical changes adverse effects of treatment Overall incidence of complications compared with non‐surgical treatment (very low certainty).

1 finding from 1 review

Surgical vs non‐surgical treatment

Patient‐reported knee instabilitya Incidence of patellar subluxation · people with lateral patellar dislocation

It is very uncertain whether surgical changes patient‐reported knee instabilitya Incidence of patellar subluxation compared with non‐surgical treatment (very low certainty).

1 finding from 1 review

Surgical vs non‐surgical treatment

Subsequent requirement for surgery (re‐operations) for complications Incidence · people with lateral patellar dislocation

It is very uncertain whether surgical changes subsequent requirement for surgery (reoperations) for complicationsa… compared with non‐surgical treatment (very low certainty).

1 finding from 1 review

Surgical vs non‐surgical treatment

Complications requiring unplanned return to theatre Subtalar arthrodesis · people aged over 14 years with displaced intra‐articular calcaneal fractures

Surgical showed no clear difference in complications requiring unplanned return to theatre Subtalar… compared with non‐surgical management (low certainty).

1 finding from 1 review