HALOPERIDOL + PROMETHAZINE vs lorazepam
- Haloperidol plus promethazine for psychosis‐induced aggression 2016 · Cochrane Headline outcomes onlyno estimate extracted0 studies · 0 participantsGRADE not reported
It is very uncertain whether ZUCLOPENTHIXOL DIHYDROCHLORIDE changes adverse effects: Sedation compared with PLACEBO (very low certainty).
FLUPHENAZINE leads to lower adverse effects‐other‐sedation compared with LOW‐POTENCY ANTIPSYCHOTIC DRUGS (high certainty).
HALOPERIDOL probably leads to lower adverse effects ‐ other ‐ Sedation compared with LOW‐POTENCY ANTIPSYCHOTIC DRUGS (moderate certainty).
QUETIAPINE probably leads to lower adverse effects: 1. Sedation compared with CLOZAPINE ‐ all data short term (moderate certainty).
QUETIAPINE showed no clear difference in adverse effects: 1. Sedation compared with OLANZAPINE (moderate certainty).
QUETIAPINE led to higher adverse effects: 1. Sedation compared with RISPERIDONE; GRADE not reported.
QUETIAPINE may leads to higher adverse effects: 1. Sedation compared with ZIPRASIDONE (low certainty).
ZUCLOPENTHIXOL ACETATE showed no clear difference in sedation/tranquillisation: Not sedated ‐ at four hours compared with STANDARD DRUG CARE (low certainty).
BENZODIAZEPINES showed no clear difference in desired sedation ‐ ultra short term ‐ asleep at 12 hours compared with ANTIPSYCHOTICS (low certainty).
ADJUNCTIVE BENZODIAZEPINES + ANTIPSYCHOTICS may leads to higher desired sedation ‐ ultra short term ‐ tranquillised at 60 minutes compared with PLACEBO/NO ADJUNCTIVE TREATMENT + ANTIPSYCHOTICS (low certainty).
ADJUNCTIVE BENZODIAZEPINES + ANTIPSYCHOTICS showed no clear difference in desired sedation ‐ ultra short term ‐ asleep at 12 hours compared with PLACEBO/NO ADJUNCTIVE TREATMENT + ANTIPSYCHOTICS (low certainty).
The review found no eligible studies for this question.