Cochrane · systematic review · CD009230
Fluphenazine versus low‐potency first‐generation antipsychotic drugs for schizophrenia
Tardy, M, Huhn, M, Engel, RR, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
SchizophreniaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 2 · 28.6%Very low 0 · 0%Low 1 · 14.3%Moderate 3 · 42.9%High 1 · 14.3%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
FLUPHENAZINE versus LOW‐POTENCY ANTIPSYCHOTIC DRUGS for schizophrenia
Population: patients with schizophrenia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Response to treatment FLUPHENAZINE vs LOW‐POTENCY ANTIPSYCHOTIC DRUGS | RR 1.03 [0.73, 1.45] | 2 studies · 103 participants | Moderate Downgraded: risk of bias |
Acceptability of treatment‐leaving the study early due to any reason FLUPHENAZINE vs LOW‐POTENCY ANTIPSYCHOTIC DRUGS | RR 1 [0.88, 1.14] | 6 studies · 1532 participants | Moderate Downgraded: risk of bias |
Adverse effects‐at least one adverse effect FLUPHENAZINE vs LOW‐POTENCY ANTIPSYCHOTIC DRUGS | RR 0.79 [0.58, 1.07] | 1 study · 65 participants | Moderate Downgraded: risk of bias |
Adverse effects‐movement disorders‐at least one movement disorder FLUPHENAZINE vs LOW‐POTENCY ANTIPSYCHOTIC DRUGS | RR 2.11 [1.41, 3.15] | 3 studies · 971 participants | Low Downgraded: risk of bias, imprecision |
Adverse effects‐other‐sedation FLUPHENAZINE vs LOW‐POTENCY ANTIPSYCHOTIC DRUGS | RR 0.31 [0.13, 0.77] | 1 study · 65 participants | High |
Adverse effects‐death FLUPHENAZINE vs LOW‐POTENCY ANTIPSYCHOTIC DRUGS | no estimate extracted | 0 studies · 0 participants | Ungraded |
Quality of life FLUPHENAZINE vs LOW‐POTENCY ANTIPSYCHOTIC DRUGS | no estimate extracted | 0 studies · 0 participants | Ungraded |