Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

121 questions · 122 findings · 25 reviews · Schizophrenia

No studies found 25 · 20.5%GRADE not reported 14 · 11.5%Very low 52 · 42.6%Low 24 · 19.7%Moderate 7 · 5.7%High 0 · 0%

Extended specialised early intervention (SEI) teams vs standard SEI teams plus treatment

Service use: admission to psychiatric hospital (assessed by proportion admitted at end of treatment) · recent‐onset psychosis

Extended specialised early intervention (SEI) teams showed no clear difference in service use: admission to psychiatric hospital at end of treatment… compared with standard SEI teams plus treatment (low certainty).

1 finding from 1 review

Specialised early intervention (SEI) vs treatment

Service use: admission to psychiatric hospital (assessed by proportion admitted at end of treatment) · recent‐onset psychosis (less than three years since the start of psychotic symptoms and either first or second psychotic episode)

Specialised early intervention (SEI) showed no clear difference in service use: admission to psychiatric hospital (assessed by… compared with treatment (low certainty).

1 finding from 1 review

CHLORPROMAZINE vs RESERPINE

Mental state: Not improved (paranoid distortion) Multidimentional Scale for Rating Psychiatric Patients (short term) · patients with schizophrenia

It is very uncertain whether CHLORPROMAZINE changes mental state: Not improved (paranoid distortion) Multidimentional… compared with RESERPINE (very low certainty).

1 finding from 1 review

User‐held information vs standard information

Psychiatric hospital admission: psychiatric admission Numbers admitted · patients with routine care of people with severe mental illness

User‐held information showed no clear difference in psychiatric hospital admission: psychiatric admission Numbers admitted compared with standard information (moderate certainty).

1 finding from 1 review

User‐held information vs standard information

Psychiatric hospital admission: compulsory admission Numbers admitted · patients with routine care of people with severe mental illness

User‐held information showed no clear difference in psychiatric hospital admission: compulsory admission Numbers admitted compared with standard information (moderate certainty).

1 finding from 1 review