Cochrane · systematic review · CD013287
Specialised early intervention teams (extended time) for recent‐onset psychosis
Puntis, S, Minichino, A, De Crescenzo, F, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
SchizophreniaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 42.9%Low 4 · 57.1%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Extended specialised early intervention (SEI) teams compared to standard SEI teams plus treatment as usual (TAU) for recent‐onset psychosis
Population: recent‐onset psychosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Global state: recovery (assessed by symptom remission over a specified time period, as defined by study) Extended specialised early intervention (SEI) teams vs standard SEI teams plus treatment | RR 1.13 [0.97, 1.31] | 3 studies · 780 participants | Very low Downgraded: imprecision, indirectness |
Service use: disengagement from services(assessment varied) Extended specialised early intervention (SEI) teams vs standard SEI teams plus treatment | RR 0.45 [0.27, 0.75] | 2 studies · 380 participants | Low Downgraded: indirectness |
Service use: admission to psychiatric hospital at end of treatment (assessed by patient records) Extended specialised early intervention (SEI) teams vs standard SEI teams plus treatment | RR 1.55 [0.68, 3.52] | 1 study · 160 participants | Low Downgraded: imprecision |
Service use: number of days in psychiatric hospital at end of treatment(assessed by patient records) Extended specialised early intervention (SEI) teams vs standard SEI teams plus treatment | no estimate extracted | 1 study · 400 participants | Low Downgraded: imprecision |
Mental state: global psychotic symptoms, average endpoint score on specific symptoms mental state scale(assessed by structured interview) Extended specialised early intervention (SEI) teams vs standard SEI teams plus treatment | no estimate extracted | 1 study · 156 participants | Very low Downgraded: imprecision, indirectness |
Adverse effects/events: death ‐ all‐cause mortality(assessed by patient records) Extended specialised early intervention (SEI) teams vs standard SEI teams plus treatment | RR 0.38 [0.09, 1.64] | 3 studies · 780 participants | Low Downgraded: imprecision |
Functioning: average endpoint score on specific functioning scale(assessed by structured interview) Extended specialised early intervention (SEI) teams vs standard SEI teams plus treatment | no estimate extracted | 2 studies · 560 participants | Very low Downgraded: imprecision, inconsistency |