Number of people experiencing one or more exacerbations, Drug resistance/microbial sensitivity (as reported by trialists), including emergence of atypical bacteria, Number of participants colonised with Pseudomonas aeruginosa · patients with chronic obstructive pulmonary disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Exacerbations (number of people experiencing ≥ 1 exacerbations) · patients with chronic obstructive pulmonary disease
Quinolone showed no clear difference in number of participants experiencing one or more exacerbations… compared with tetracycline (low certainty).
1 finding from 1 review
Exacerbations (number of people experiencing ≥ 1 exacerbations) · patients with chronic obstructive pulmonary disease
Quinolone showed no clear difference in number of participants experiencing one or more exacerbations… compared with macrolide (low certainty).
1 finding from 1 review
Exacerbations · people with asthma
Tailored interventions based on sputum eosinophils probably leads to lower number of participants who had one or more exacerbations over the… compared with tailored interventions based on clinical symptoms (moderate certainty).
1 finding from 1 review
Intervention not reported
Number of participants who had one or more exacerbation of the study period · Adults from minority groups with doctor diagnosed asthma
It is very uncertain whether the intervention changes number of participants who had one or more exacerbation of the study… (very low certainty).
1 finding from 1 review
Intervention not reported
% change from baseline ICS dose Duration of trials: 12 to 24 weeks More reduction is better · adults and adolescents with persistent asthma
1 finding from 1 review
Exacerbations (OCS) · people with asthma
Simplified showed no clear difference in exacerbations requiring OCS People with 1 or more compared with usual regimens (low certainty).
1 finding from 1 review
Exacerbations (OCS) · people with asthma
Adherence education showed no clear difference in exacerbations requiring OCS (people with 1 or more) WMD of compared with controls (low certainty).
1 finding from 1 review
Unscheduled visits 1 or more hospitalisations for any cause WMD of · children with asthma
School‐based ICS therapy showed no clear difference in unscheduled visits 1 or more hospitalisations for any cause WMD of compared with home therapy (low certainty).
1 finding from 1 review
Unsheduled visits to a healthcare provider (people with 1 or more) WMD of · people with asthma
It is very uncertain whether adherence education changes unsheduled visits to a healthcare provider (people with 1 or more)… compared with controls (very low certainty).
1 finding from 1 review
Intervention not reported
Serious Adverse Events (Participants with one or more event) · Adults (>18 years) with pulmonary hypertension of varied aetiology (PAH, CTEPH and left heart disease)
It is very uncertain whether the intervention changes serious Adverse Events (Participants with one or more event) (very low certainty).
1 finding from 1 review
Number of participants experiencing one or more episode requiring treatment with oral steroids · episodic viral wheeze in children
Maintenance LTRA showed no clear difference in number of participants experiencing one or more episode requiring… compared with placebo (moderate certainty).
1 finding from 1 review
Number of participants experiencing one or more episodes requiring ED visit · episodic viral wheeze in children
Maintenance LTRA showed no clear difference in number of participants experiencing one or more episodes requiring… compared with placebo (moderate certainty).
1 finding from 1 review
Number of participants experiencing one or more episodes requiring hospital admission · episodic viral wheeze in children
Maintenance LTRA showed no clear difference in number of participants experiencing one or more episodes requiring… compared with placebo (moderate certainty).
1 finding from 1 review
Number of participants experiencing one or more episode requiring treatment with oral steroids · episodic viral wheeze in children
Intermittent LTRA showed no clear difference in number of participants experiencing one or more episode requiring… compared with placebo (moderate certainty).
1 finding from 1 review
Number of participants experiencing one or more episodes requiring ED visit · episodic viral wheeze in children
Intermittent LTRA showed no clear difference in number of participants experiencing one or more episodes requiring… compared with placebo (moderate certainty).
1 finding from 1 review
Number of participants experiencing one or more episodes requiring hospital admission · episodic viral wheeze in children
Intermittent LTRA showed no clear difference in number of participants experiencing one or more episodes requiring… compared with placebo (moderate certainty).
1 finding from 1 review
Exacerbations · chronic obstructive pulmonary disease (COPD). Participants in included studies had an average baseline FEV1 of around 40% predicted and…
Tiotropium leads to lower patients with one or more exacerbations compared with ipratropium (high certainty).
1 finding from 1 review
Exacerbations (number of people experiencing ≥ 1 exacerbations) · patients with chronic obstructive pulmonary disease
Indacaterol leads to lower number of participants experiencing 1 or more exacerbations compared with placebo (high certainty).
1 finding from 1 review
Hospitalisations Number of participants experiencing one of more hospitalisations. · people with bronchiectasis
Inhaled mannitol showed no clear difference in hospitalisations Number of participants experiencing one of more… compared with placebo (moderate certainty).
1 finding from 1 review