Cochrane · systematic review · CD012226
Interventions to improve adherence to inhaled steroids for asthma
Normansell, R, Kew, KM, Stovold, E · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
24
current version
GRADE rated
22
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 2 · 8.3%Very low 2 · 8.3%Low 11 · 45.8%Moderate 9 · 37.5%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Adherence education compared with controls for asthma
Population: asthma
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
% Adherence WMD of Adherence education vs controls | no estimate extracted | 5 studies · 280 participants | Low Downgraded: risk of bias |
Exacerbations requiring OCS (people with 1 or more) WMD of Adherence education vs controls | OR 1.82 [0.99, 3.36] | 3 studies · 349 participants | Low Downgraded: risk of bias |
Asthma control (ACQ) WMD of Adherence education vs controls | no estimate extracted | 4 studies · 455 participants | Moderate Downgraded: risk of bias |
Asthma control (ACT) WMD of Adherence education vs controls | no estimate extracted | 3 studies · 333 participants | Moderate Downgraded: risk of bias |
Unsheduled visits to a healthcare provider (people with 1 or more) WMD of Adherence education vs controls | OR 0.48 [0.19, 1.19] | 4 studies · 688 participants | Very low Downgraded: risk of bias |
Absenteeism WMD of Adherence education vs controls | no estimate extracted | 2 studies · 109 participants | Ungraded |
Quality of life (AQLQ) WMD of Adherence education vs controls | no estimate extracted | 6 studies · 734 participants | Moderate Downgraded: risk of bias |
Electronic trackers or reminders (± feedback) compared with controls for asthma
Population: asthma
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
% Adherence WMD of Electronic trackers or reminders (± feedback) vs controls | no estimate extracted | 6 studies · 555 participants | Moderate Downgraded: risk of bias |
Exacerbations requiring OCS (people with at least 1) WMD of Electronic trackers or reminders (± feedback) vs controls | OR 0.72 [0.37, 1.39] | 4 studies · 3063 participants | Very low Downgraded: risk of bias |
Asthma control (ACQ) WMD of Electronic trackers or reminders (± feedback) vs controls | no estimate extracted | 2 studies · 109 participants | Low Downgraded: risk of bias |
Asthma control (ACT) WMD of Electronic trackers or reminders (± feedback) vs controls | no estimate extracted | 4 studies · 596 participants | Low Downgraded: risk of bias |
Unscheduled healthcare visits to a healthcare provider (ED) WMD of Electronic trackers or reminders (± feedback) vs controls | OR 1.14 [0.88, 1.47] | 2 studies · 2918 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Absenteeism (people with at least 1 absence) Electronic trackers or reminders (± feedback) vs controls | OR 1.42 [0.82, 2.47] | 1 study · 220 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Quality of life (AQLQ) WMD of Electronic trackers or reminders (± feedback) vs controls | no estimate extracted | 4 studies · 369 participants | Moderate Downgraded: risk of bias |
Simplified compared with usual regimens for asthma
Population: asthma
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
% Adherence (objective measures) WMD of Simplified vs usual regimens | no estimate extracted | 3 studies · 1310 participants | Moderate Downgraded: risk of bias |
Exacerbations requiring OCS People with 1 or more Simplified vs usual regimens | OR 2.33 [0.17, 32.58] | 1 study · 16 participants | Low Downgraded: risk of bias, imprecision |
Asthma control (ACQ) Simplified vs usual regimens | no estimate extracted | 1 study · 103 participants | Moderate Downgraded: risk of bias, imprecision |
Unscheduled visits Simplified vs usual regimens | OR 1.17 [0.72, 1.9] | 1 study · 1037 participants | Low Downgraded: risk of bias |
Absence from work/school Simplified vs usual regimens | OR 0.93 [0.37, 2.3] | 1 study · 1037 participants | Low Downgraded: risk of bias |
Change in quality of life (ITG‐ASF) Simplified vs usual regimens | no estimate extracted | 1 study · 1037 participants | Low Downgraded: risk of bias |
All adverse events Simplified vs usual regimens | OR 0.76 [0.56, 1.04] | 1 study · 1233 participants | Low Downgraded: risk of bias |
School‐based ICS therapy compared with home therapy for asthma
Population: children with asthma
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Unscheduled visits 1 or more hospitalisations for any cause WMD of School‐based ICS therapy vs home therapy | OR 0.58 [0.16, 2.05] | 2 studies · 279 participants | Low Downgraded: risk of bias |
Quality of life (PACQLQ) School‐based ICS therapy vs home therapy | no estimate extracted | 2 studies · 279 participants | Moderate Downgraded: risk of bias |
Adverse events School‐based ICS therapy vs home therapy | no estimate extracted | 1 study · 99 participants | Ungraded |