Question · asked by 1 review

Maintenance LTRA vs placebo: Number of participants experiencing one or more episodes requiring hospital admission

Maintenance LTRA showed no clear difference in number of participants experiencing one or more episodes requiring… compared with placebo (moderate certainty).

What each review found

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FindingEffectStudiesGRADE certainty
Maintenance LTRA vs placebo
Number of participants experiencing one or more episodes requiring hospital admission · episodic viral wheeze in children
Maintenance LTRA showed no clear difference in number of participants experiencing one or more episodes requiring… compared with placebo (moderate certainty).
Leukotriene receptor antagonists as maintenance and intermittent therapy for episodic viral wheeze in children (2015) · Cochrane Headline outcomes only
OR 0.65 [0.23, 1.87]1 study · 347 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Leukotriene receptor antagonists as maintenance and intermittent therapy for episodic viral wheeze in children
2015 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.